Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4381689..4382254 Replicon chromosome
Accession NZ_CP027668
Organism Phreatobacter cathodiphilus strain S-12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6569_RS21065 Protein ID WP_106750703.1
Coordinates 4381689..4381979 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6569_RS21070 Protein ID WP_106750704.1
Coordinates 4381967..4382254 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6569_RS21040 4377185..4377790 + 606 WP_106750699.1 shikimate kinase -
C6569_RS21045 4377799..4378935 + 1137 WP_106751180.1 3-dehydroquinate synthase -
C6569_RS21050 4379040..4380323 + 1284 WP_106750700.1 HlyC/CorC family transporter -
C6569_RS21055 4380352..4380732 + 381 WP_106750701.1 methylglyoxal synthase -
C6569_RS21060 4380824..4381681 + 858 WP_106750702.1 crotonase/enoyl-CoA hydratase family protein -
C6569_RS21065 4381689..4381979 - 291 WP_106750703.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6569_RS21070 4381967..4382254 - 288 WP_106750704.1 CopG family ribbon-helix-helix protein Antitoxin
C6569_RS21075 4382411..4383577 + 1167 WP_106750705.1 amidohydrolase -
C6569_RS21080 4383586..4384566 + 981 WP_106751181.1 Gfo/Idh/MocA family oxidoreductase -
C6569_RS21085 4385034..4386659 - 1626 WP_106750706.1 GMC family oxidoreductase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-44)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10808.52 Da        Isoelectric Point: 11.6182

>T99837 WP_106750703.1 NZ_CP027668:c4381979-4381689 [Phreatobacter cathodiphilus]
MPRVIIAAGAVAGLERCRRFLAARDRRASQRAAAEIRRHFSALERLPGMGRPVGREGLRELVIPFGAAGYVALYRHEPDE
DRVLILAFRHQREAGY

Download         Length: 291 bp

>T99837 NZ_CP027668:c4381979-4381689 [Phreatobacter cathodiphilus]
TTGCCACGAGTGATCATCGCAGCGGGCGCGGTCGCCGGCCTCGAACGATGCCGGCGCTTCCTCGCGGCCCGCGATCGCCG
GGCCTCGCAGCGGGCCGCGGCGGAGATACGCCGGCATTTCTCGGCGCTCGAGCGGTTGCCTGGCATGGGGCGGCCGGTGG
GTCGCGAGGGGCTTCGTGAACTGGTCATCCCCTTCGGAGCCGCAGGCTACGTCGCTCTCTATCGTCACGAGCCGGATGAG
GATCGGGTGCTGATCCTGGCATTCCGCCACCAGCGGGAAGCCGGATACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10944.14 Da        Isoelectric Point: 4.6620

>AT99837 WP_106750704.1 NZ_CP027668:c4382254-4381967 [Phreatobacter cathodiphilus]
MAAGKATTTLKLDETLKERVRQLAEARQRTPHWIMREAIADYVQREEAREAFQREAMDSWRAFRETGEHLTGTEVDAWLA
GWGTEDEAEAPVCHE

Download         Length: 288 bp

>AT99837 NZ_CP027668:c4382254-4381967 [Phreatobacter cathodiphilus]
ATGGCGGCAGGCAAGGCCACGACGACGCTGAAGCTGGACGAGACGCTGAAGGAGCGCGTCCGGCAGCTGGCCGAGGCGCG
CCAGCGAACACCCCACTGGATCATGCGCGAGGCCATCGCGGATTATGTCCAGCGCGAGGAGGCGCGTGAAGCCTTCCAGC
GCGAGGCGATGGACTCCTGGCGGGCCTTCCGCGAGACGGGAGAGCATCTGACAGGCACCGAAGTCGATGCCTGGCTGGCC
GGCTGGGGCACAGAAGACGAGGCCGAGGCTCCCGTTTGCCACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References