Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4381689..4382254 Replicon chromosome
Accession NZ_CP027668
Organism Phreatobacter cathodiphilus strain S-12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6569_RS21065 Protein ID WP_106750703.1
Coordinates 4381689..4381979 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6569_RS21070 Protein ID WP_106750704.1
Coordinates 4381967..4382254 (-) Length 96 a.a.

Genomic Context

C6569_RS21040C6569_RS21045C6569_RS21050C6569_RS21055C6569_RS21060C6569_RS21075C6569_RS21080C6569_RS21065C6569_RS21070C6569_RS21085
Location: 4377185..4377790 (606 bp)
Type: Others
Protein ID: WP_106750699.1
Location: 4377799..4378935 (1137 bp)
Type: Others
Protein ID: WP_106751180.1
Location: 4379040..4380323 (1284 bp)
Type: Others
Protein ID: WP_106750700.1
Location: 4380352..4380732 (381 bp)
Type: Others
Protein ID: WP_106750701.1
Location: 4380824..4381681 (858 bp)
Type: Others
Protein ID: WP_106750702.1
Location: 4382411..4383577 (1167 bp)
Type: Others
Protein ID: WP_106750705.1
Location: 4383586..4384566 (981 bp)
Type: Others
Protein ID: WP_106751181.1
Location: 4381689..4381979 (291 bp)
Type: Toxin
Protein ID: WP_106750703.1
Location: 4381967..4382254 (288 bp)
Type: Antitoxin
Protein ID: WP_106750704.1
Location: 4385034..4386659 (1626 bp)
Type: Others
Protein ID: WP_106750706.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C6569_RS210404377185..4377790+606WP_106750699.1shikimate kinase-
C6569_RS210454377799..4378935+1137WP_106751180.13-dehydroquinate synthase-
C6569_RS210504379040..4380323+1284WP_106750700.1HlyC/CorC family transporter-
C6569_RS210554380352..4380732+381WP_106750701.1methylglyoxal synthase-
C6569_RS210604380824..4381681+858WP_106750702.1crotonase/enoyl-CoA hydratase family protein-
C6569_RS210654381689..4381979-291WP_106750703.1type II toxin-antitoxin system RelE/ParE family toxinToxin
C6569_RS210704381967..4382254-288WP_106750704.1CopG family ribbon-helix-helix proteinAntitoxin
C6569_RS210754382411..4383577+1167WP_106750705.1amidohydrolase-
C6569_RS210804383586..4384566+981WP_106751181.1Gfo/Idh/MocA family oxidoreductase-
C6569_RS210854385034..4386659-1626WP_106750706.1GMC family oxidoreductase N-terminal domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-44)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10808.52 Da        Isoelectric Point: 11.6182

>T99837 WP_106750703.1 NZ_CP027668:c4381979-4381689 [Phreatobacter cathodiphilus]
MPRVIIAAGAVAGLERCRRFLAARDRRASQRAAAEIRRHFSALERLPGMGRPVGREGLRELVIPFGAAGYVALYRHEPDE
DRVLILAFRHQREAGY

Download         Length: 291 bp

>T99837 NZ_CP027668:c4381979-4381689 [Phreatobacter cathodiphilus]
TTGCCACGAGTGATCATCGCAGCGGGCGCGGTCGCCGGCCTCGAACGATGCCGGCGCTTCCTCGCGGCCCGCGATCGCCG
GGCCTCGCAGCGGGCCGCGGCGGAGATACGCCGGCATTTCTCGGCGCTCGAGCGGTTGCCTGGCATGGGGCGGCCGGTGG
GTCGCGAGGGGCTTCGTGAACTGGTCATCCCCTTCGGAGCCGCAGGCTACGTCGCTCTCTATCGTCACGAGCCGGATGAG
GATCGGGTGCTGATCCTGGCATTCCGCCACCAGCGGGAAGCCGGATACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10944.14 Da        Isoelectric Point: 4.6620

>AT99837 WP_106750704.1 NZ_CP027668:c4382254-4381967 [Phreatobacter cathodiphilus]
MAAGKATTTLKLDETLKERVRQLAEARQRTPHWIMREAIADYVQREEAREAFQREAMDSWRAFRETGEHLTGTEVDAWLA
GWGTEDEAEAPVCHE

Download         Length: 288 bp

>AT99837 NZ_CP027668:c4382254-4381967 [Phreatobacter cathodiphilus]
ATGGCGGCAGGCAAGGCCACGACGACGCTGAAGCTGGACGAGACGCTGAAGGAGCGCGTCCGGCAGCTGGCCGAGGCGCG
CCAGCGAACACCCCACTGGATCATGCGCGAGGCCATCGCGGATTATGTCCAGCGCGAGGAGGCGCGTGAAGCCTTCCAGC
GCGAGGCGATGGACTCCTGGCGGGCCTTCCGCGAGACGGGAGAGCATCTGACAGGCACCGAAGTCGATGCCTGGCTGGCC
GGCTGGGGCACAGAAGACGAGGCCGAGGCTCCCGTTTGCCACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References