Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3217680..3218483 Replicon chromosome
Accession NZ_CP027668
Organism Phreatobacter cathodiphilus strain S-12

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag C6569_RS15450 Protein ID WP_106749677.1
Coordinates 3217680..3218180 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag C6569_RS15455 Protein ID WP_106749678.1
Coordinates 3218184..3218483 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6569_RS15430 3213994..3214869 - 876 WP_106749674.1 F0F1 ATP synthase subunit gamma -
C6569_RS15435 3214869..3215237 - 369 WP_106751083.1 PH domain-containing protein -
C6569_RS15440 3215332..3216861 - 1530 WP_106749675.1 F0F1 ATP synthase subunit alpha -
C6569_RS15445 3216861..3217421 - 561 WP_106749676.1 F0F1 ATP synthase subunit delta -
C6569_RS15450 3217680..3218180 - 501 WP_106749677.1 GNAT family N-acetyltransferase Toxin
C6569_RS15455 3218184..3218483 - 300 WP_106749678.1 DUF1778 domain-containing protein Antitoxin
C6569_RS15460 3218612..3220819 - 2208 WP_106749679.1 enoyl-CoA hydratase/isomerase family protein -
C6569_RS15465 3220834..3222042 - 1209 WP_106749680.1 acetyl-CoA C-acetyltransferase -
C6569_RS15470 3222113..3223270 - 1158 WP_106749681.1 acyl-CoA dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-143)

Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 17646.36 Da        Isoelectric Point: 8.7704

>T99836 WP_106749677.1 NZ_CP027668:c3218180-3217680 [Phreatobacter cathodiphilus]
VALSAPEILTAAHDVAAFSCGKPALDNWIRTRALSNQEKGFTAVLVVHEAGRVVGYYGLAPTAVIPGTMPRSIRTGQPPD
PVPCLVLGQLATDRAWAGRGIGTGLLKHALSRCVDAATLVGGRALLVHAVDDEAADFWRRRGFLPSRDDPFILFRSIPAI
AASLRE

Download         Length: 501 bp

>T99836 NZ_CP027668:c3218180-3217680 [Phreatobacter cathodiphilus]
GTGGCCCTGTCGGCCCCGGAAATCCTCACGGCCGCCCACGACGTCGCCGCTTTTTCCTGCGGAAAGCCCGCACTCGACAA
TTGGATCAGAACGCGAGCCCTTTCCAACCAGGAGAAGGGCTTCACGGCCGTGCTGGTCGTCCATGAGGCCGGCCGGGTCG
TCGGCTATTACGGCCTTGCCCCGACCGCGGTGATCCCCGGCACCATGCCGCGCTCCATCAGGACCGGACAGCCGCCTGAC
CCCGTGCCATGCCTGGTGCTGGGCCAACTCGCCACGGATCGCGCGTGGGCCGGCCGGGGAATCGGCACGGGCCTGCTCAA
GCATGCGCTGTCCCGCTGCGTCGATGCGGCAACCCTCGTGGGCGGACGGGCGCTGCTGGTCCATGCGGTCGACGATGAGG
CTGCCGATTTCTGGCGACGACGCGGCTTTCTTCCCTCCAGGGACGACCCATTCATCCTCTTTCGCAGCATCCCGGCCATC
GCAGCCTCGCTCCGGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10884.55 Da        Isoelectric Point: 5.7252

>AT99836 WP_106749678.1 NZ_CP027668:c3218483-3218184 [Phreatobacter cathodiphilus]
MTAKSARSDHPISMRLPEADIAMIDRAAGLRGRSRTDFVREAAVRAAEDVLMEQHLIRMSPEGFTAFLAVLETPAAPVPE
MVDLVKRRAPWEAIPASES

Download         Length: 300 bp

>AT99836 NZ_CP027668:c3218483-3218184 [Phreatobacter cathodiphilus]
ATGACCGCCAAGAGCGCCCGTAGCGACCACCCCATTTCGATGCGCCTGCCCGAGGCCGATATCGCGATGATCGACCGCGC
CGCCGGGCTGCGCGGGAGAAGCCGTACGGATTTCGTGCGCGAGGCGGCTGTTCGTGCAGCCGAGGACGTGCTGATGGAAC
AGCACCTTATCCGCATGAGCCCCGAGGGCTTCACCGCTTTTCTGGCCGTGCTCGAGACGCCGGCCGCGCCCGTTCCGGAG
ATGGTTGATCTGGTGAAGAGGCGCGCTCCCTGGGAAGCAATCCCAGCTTCCGAAAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References