Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 966218..966723 Replicon chromosome
Accession NZ_CP027668
Organism Phreatobacter cathodiphilus strain S-12

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C6569_RS04665 Protein ID WP_106747742.1
Coordinates 966218..966472 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6569_RS04670 Protein ID WP_106747743.1
Coordinates 966469..966723 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6569_RS04645 962744..963067 - 324 WP_106747739.1 rhodanese-like domain-containing protein -
C6569_RS04650 963146..964237 - 1092 WP_106747740.1 anhydro-N-acetylmuramic acid kinase -
C6569_RS04655 964338..965591 + 1254 WP_106747741.1 tyrosine--tRNA ligase -
C6569_RS04660 965602..966213 + 612 WP_106750897.1 glutathione S-transferase N-terminal domain-containing protein -
C6569_RS04665 966218..966472 - 255 WP_106747742.1 Txe/YoeB family addiction module toxin Toxin
C6569_RS04670 966469..966723 - 255 WP_106747743.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C6569_RS04675 966755..967336 - 582 WP_106747744.1 3-isopropylmalate dehydratase small subunit -
C6569_RS04680 967333..968736 - 1404 WP_106747745.1 3-isopropylmalate dehydratase large subunit -
C6569_RS04685 968913..969719 + 807 WP_106747746.1 GntR family transcriptional regulator -
C6569_RS04690 969815..971032 + 1218 WP_106747747.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10342.89 Da        Isoelectric Point: 9.5787

>T99835 WP_106747742.1 NZ_CP027668:c966472-966218 [Phreatobacter cathodiphilus]
MTVAFHPLAWEDYLHWQEADRRILKKLNALIRECRRTPFTGTGKPEPLKNEFQGWWSRRIDQEHRLVYRMRGEVLEIAQC
RYHY

Download         Length: 255 bp

>T99835 NZ_CP027668:c966472-966218 [Phreatobacter cathodiphilus]
ATGACCGTCGCGTTCCACCCCCTTGCTTGGGAGGATTACCTGCACTGGCAGGAGGCAGATCGCAGGATTCTTAAGAAGCT
GAACGCCTTGATCCGCGAGTGCCGACGCACGCCGTTCACCGGCACCGGCAAGCCGGAGCCGCTGAAGAACGAATTCCAGG
GCTGGTGGTCGCGGCGGATCGACCAGGAGCACCGCCTCGTCTACCGCATGCGCGGCGAGGTGCTCGAGATCGCCCAGTGC
CGCTACCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9324.67 Da        Isoelectric Point: 5.1425

>AT99835 WP_106747743.1 NZ_CP027668:c966723-966469 [Phreatobacter cathodiphilus]
MRVKTSTELRKTLAATLDQVTADHAPVLITREGGKPPAVLISLEDYTSMEETTYLTKSPENRRRLLEAITGLDEGKGIVR
DLLE

Download         Length: 255 bp

>AT99835 NZ_CP027668:c966723-966469 [Phreatobacter cathodiphilus]
ATGCGCGTCAAGACCTCGACCGAACTCCGCAAGACCCTCGCCGCCACCCTCGACCAGGTGACGGCGGACCATGCGCCGGT
GCTGATCACCCGCGAGGGCGGCAAGCCGCCCGCGGTGCTGATCTCGCTGGAGGACTACACGTCGATGGAAGAGACGACCT
ATCTGACGAAGAGCCCCGAGAACCGTCGGCGCCTGCTGGAAGCGATCACCGGGCTCGATGAGGGCAAAGGCATCGTGCGC
GATCTCCTGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References