Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2344571..2345163 Replicon chromosome
Accession NZ_CP027667
Organism Melaminivora sp. SC2-9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6568_RS11060 Protein ID WP_106684162.1
Coordinates 2344867..2345163 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6568_RS11055 Protein ID WP_106684161.1
Coordinates 2344571..2344870 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6568_RS11045 2341090..2343180 - 2091 WP_106685472.1 flagellar biosynthesis protein FlhA -
C6568_RS11050 2343201..2344376 - 1176 WP_106684160.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -
C6568_RS11055 2344571..2344870 - 300 WP_106684161.1 putative addiction module antidote protein Antitoxin
C6568_RS11060 2344867..2345163 - 297 WP_106684162.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6568_RS11065 2345215..2345847 - 633 WP_106684163.1 protein phosphatase CheZ -
C6568_RS11070 2345849..2346235 - 387 WP_106684164.1 chemotaxis response regulator CheY -
C6568_RS11075 2346286..2347224 - 939 WP_106684165.1 flagellar motor protein MotB -
C6568_RS11080 2347237..2348097 - 861 WP_106684166.1 flagellar motor stator protein MotA -
C6568_RS11085 2348304..2349782 - 1479 WP_106684167.1 flagellin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11244.05 Da        Isoelectric Point: 10.3358

>T99831 WP_106684162.1 NZ_CP027667:c2345163-2344867 [Melaminivora sp. SC2-9]
MYTVVEAEAFAVWMEALRDKSTRGRLQIRLRKAGLGHLGDVRPVGDGVWEMREFFGPGWRMYYVMRGSTIVVMLGGGDKS
SQQRDIERARKMAQELHL

Download         Length: 297 bp

>T99831 NZ_CP027667:c2345163-2344867 [Melaminivora sp. SC2-9]
ATGTACACCGTCGTTGAAGCTGAGGCTTTCGCTGTCTGGATGGAAGCGCTCAGGGACAAGTCGACACGCGGCCGGTTGCA
AATTCGCCTGCGAAAAGCCGGCTTGGGTCATCTCGGTGATGTGAGGCCAGTCGGCGATGGCGTATGGGAGATGCGCGAGT
TCTTTGGTCCCGGCTGGCGCATGTATTACGTGATGCGGGGGTCCACCATCGTCGTGATGCTGGGCGGCGGCGACAAATCC
AGCCAGCAGCGCGACATCGAGCGCGCCAGGAAGATGGCGCAGGAACTGCATTTATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10599.12 Da        Isoelectric Point: 6.4627

>AT99831 WP_106684161.1 NZ_CP027667:c2344870-2344571 [Melaminivora sp. SC2-9]
MSLIKTRPFDAANYLRDEADVAAYLQAAVEDGDPALLAAVLGDIARARGMTQLARDTGLSRESLYKSLSGERAPSSETLF
KVLHALGFKLTLLHTPPAA

Download         Length: 300 bp

>AT99831 NZ_CP027667:c2344870-2344571 [Melaminivora sp. SC2-9]
ATGAGCCTCATCAAGACACGACCTTTTGACGCAGCCAACTACCTGCGCGACGAAGCCGATGTCGCGGCTTATCTGCAGGC
GGCCGTGGAGGACGGCGACCCGGCGCTGCTGGCCGCCGTCCTGGGCGACATCGCTCGCGCGCGCGGCATGACGCAACTGG
CGCGTGACACCGGCCTGTCGCGCGAGAGCCTGTACAAGAGCCTGTCGGGCGAGCGCGCCCCCAGCTCGGAGACGCTGTTC
AAGGTTTTGCACGCGCTGGGCTTCAAGCTGACGCTGCTGCACACGCCGCCGGCGGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References