Detailed information of TA system TA099830

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 2259572..2261070
• Replicon: chromosome
• Accession: NZ_CP027667
• Organism: Melaminivora sp. SC2-9

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: C6568_RS10670
• Protein ID: WP_106684099.1
• Coordinates: 2260168..2261070 (+)
• Length: 301 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: C6568_RS10665
• Protein ID: WP_106684098.1
• Coordinates: 2259572..2260171 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6568_RS10660	2257221..2259398	+	2178	WP_106684097.1	hypothetical protein	-
C6568_RS10665	2259572..2260171	+	600	WP_106684098.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
C6568_RS10670	2260168..2261070	+	903	WP_106684099.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2240338..2270485	30147

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-256)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-52)

Sequences

Toxin

Protein

• Length: 301 a.a.
• Molecular weight: 33172.92 Da
• Isoelectric Point: 5.8847

>T99830 WP_106684099.1 NZ_CP027667:2260168-2261070 [Melaminivora sp. SC2-9]
MSANLSASILARLLTLAKQRDDDYSLLLNRFGMERLLARVSSSPYAERFLLKGALLFAMWYDTPHRPTRDADLLGFGPDD
ETNLIATFREVAAMDLDDGIVFDPESVKADAIREDNTYGGTRITLVARIGSARCALQIDVGFGDAVTPGPQTVTYPTLLD
DFQAPTLRVYPVYTVIAEKYQAMVMLGQANSRMKDFFDLTVIARRTELDGATLATAITATFARRQTALPTGRPLALTKQF
SEDPAKLRQWQAFLNKNRIAAASLGDTIALLDDLLWPPTQVAAAHSQAKATWRPDSLRWV

Nucleotide

• Length: 903 bp

>T99830 NZ_CP027667:2260168-2261070 [Melaminivora sp. SC2-9]
ATGAGCGCGAATCTTTCGGCATCCATCCTGGCCCGGTTGCTGACGCTTGCCAAACAACGGGATGACGACTACAGCCTGCT
GCTCAACCGCTTCGGCATGGAGCGCCTGCTGGCGCGCGTCAGCAGCTCACCGTATGCAGAGCGTTTCTTGCTCAAGGGTG
CGCTGCTCTTTGCGATGTGGTACGACACTCCGCACCGCCCGACACGGGATGCCGACCTGCTGGGCTTCGGCCCTGATGAT
GAGACAAACCTGATAGCCACTTTCCGCGAAGTCGCTGCCATGGACCTGGACGATGGCATCGTGTTTGACCCGGAATCCGT
GAAAGCCGATGCCATTCGCGAAGACAACACCTACGGCGGCACCCGCATCACGCTGGTGGCACGCATAGGCTCTGCGCGCT
GCGCCCTGCAAATCGACGTGGGCTTTGGCGATGCCGTGACGCCAGGGCCGCAGACTGTGACTTATCCCACTTTGCTGGAC
GACTTCCAAGCCCCTACGCTGCGGGTGTATCCGGTCTACACCGTGATTGCCGAGAAGTACCAGGCCATGGTGATGCTGGG
GCAGGCAAACAGCCGCATGAAAGACTTTTTCGACCTTACGGTGATTGCAAGGCGAACAGAGCTGGACGGCGCCACGCTGG
CCACAGCCATAACCGCCACCTTTGCCCGACGCCAGACAGCATTGCCTACAGGGCGCCCGCTTGCACTGACGAAACAGTTC
AGCGAAGACCCTGCCAAGCTGCGCCAGTGGCAGGCTTTCTTGAACAAGAACCGCATTGCCGCAGCCAGTTTGGGTGACAC
CATTGCGCTGCTTGACGACCTGCTGTGGCCTCCCACGCAGGTGGCTGCCGCACACAGCCAGGCGAAGGCCACTTGGCGCC
CGGATTCCTTGCGCTGGGTTTGA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22332.84 Da
• Isoelectric Point: 9.6695

>AT99830 WP_106684098.1 NZ_CP027667:2259572-2260171 [Melaminivora sp. SC2-9]
MNQSDYILELARHRRVLRAADVRAQGWSPQLLIRLHQAGKLHRLGRGLYGLPDAEVTEHQTLIEVCQRVPKAVLCLLSAL
QFHEIGTQLPHEVWVALPEGTQAPAPGYPALRITRLRGAAYSDGIQTVAEHGAPIRVYSAAKTVTDCFKFRNKIGLDVAL
EALKDAWRSRKVTMDELGHFAKINRVERVMQPYLEAVTQ

Nucleotide

• Length: 600 bp

>AT99830 NZ_CP027667:2259572-2260171 [Melaminivora sp. SC2-9]
ATGAACCAATCCGACTACATCCTTGAACTGGCCCGGCACCGGCGCGTGCTGCGGGCGGCGGATGTGCGTGCGCAAGGCTG
GTCGCCGCAGCTTTTGATTCGGCTGCACCAGGCGGGCAAGCTGCACCGGCTGGGGCGCGGTTTGTACGGGCTGCCCGACG
CCGAAGTGACCGAGCACCAGACGCTGATCGAGGTGTGCCAGCGCGTGCCCAAGGCCGTGCTGTGCCTGCTGAGCGCGTTG
CAGTTCCACGAGATCGGCACGCAACTGCCCCACGAAGTATGGGTCGCGCTGCCTGAAGGCACGCAGGCCCCGGCGCCGGG
CTACCCGGCGCTGCGCATCACGCGCCTGCGTGGCGCCGCGTACAGCGACGGCATCCAGACAGTGGCCGAGCACGGCGCCC
CAATCCGCGTGTACAGCGCCGCCAAAACGGTGACGGACTGCTTCAAGTTCCGCAACAAGATTGGCCTGGACGTGGCGCTG
GAGGCGCTGAAAGATGCATGGCGCAGCCGAAAGGTCACCATGGACGAGCTGGGCCACTTCGCCAAGATCAATCGCGTCGA
ACGTGTCATGCAGCCTTACCTGGAGGCGGTCACGCAATGA