Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1910146..1910713 Replicon chromosome
Accession NZ_CP027667
Organism Melaminivora sp. SC2-9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6568_RS09130 Protein ID WP_106683838.1
Coordinates 1910384..1910713 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6568_RS09125 Protein ID WP_106683837.1
Coordinates 1910146..1910397 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6568_RS09100 1906413..1906634 - 222 WP_106683832.1 DUF350 domain-containing protein -
C6568_RS09105 1906693..1908201 - 1509 WP_106683833.1 DUF4178 domain-containing protein -
C6568_RS09110 1908267..1909319 - 1053 WP_106683834.1 SPFH domain-containing protein -
C6568_RS09115 1909482..1909760 + 279 WP_106683835.1 DUF2061 domain-containing protein -
C6568_RS09120 1909721..1910023 - 303 WP_106683836.1 flagellar basal body rod protein -
C6568_RS09125 1910146..1910397 + 252 WP_106683837.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C6568_RS09130 1910384..1910713 + 330 WP_106683838.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
C6568_RS09135 1910717..1911655 - 939 WP_106683839.1 LysR family transcriptional regulator -
C6568_RS09140 1911761..1913125 + 1365 WP_106683840.1 aspartate aminotransferase family protein -
C6568_RS09145 1913205..1914722 + 1518 WP_106683841.1 CoA-acylating methylmalonate-semialdehyde dehydrogenase -
C6568_RS09150 1914824..1915684 - 861 WP_106683842.1 FadR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(31-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-72)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12249.33 Da        Isoelectric Point: 10.2647

>T99827 WP_106683838.1 NZ_CP027667:1910384-1910713 [Melaminivora sp. SC2-9]
MTASEPAPGSPRYRLQFLPEALDEWNALDGSVKDVLRKLLKKRLLQPHVPGARLHADLRGCYKIKLRQQGWRLVYQVEDD
VLVVLVLAVSKREGMAAYRAAVDRLLGGS

Download         Length: 330 bp

>T99827 NZ_CP027667:1910384-1910713 [Melaminivora sp. SC2-9]
TTGACAGCCTCTGAGCCCGCGCCCGGCTCGCCGCGCTACCGCCTCCAGTTCCTGCCCGAAGCCCTGGACGAGTGGAATGC
GCTGGATGGCAGCGTGAAGGACGTGCTGCGCAAGCTGCTGAAAAAGCGTTTGCTGCAACCCCACGTGCCCGGCGCCCGGC
TGCACGCGGACTTGCGCGGCTGCTACAAGATCAAACTGCGCCAGCAGGGCTGGCGCCTGGTGTACCAGGTCGAGGACGAC
GTGCTCGTCGTGCTGGTGCTGGCCGTGTCCAAACGCGAAGGCATGGCGGCCTACCGCGCGGCCGTTGACCGCCTGCTGGG
CGGCTCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9415.77 Da        Isoelectric Point: 5.0348

>AT99827 WP_106683837.1 NZ_CP027667:1910146-1910397 [Melaminivora sp. SC2-9]
MDNIYADYSISMSEFKKNPAQVLRTAGEKPVAVLNHNRPAFYMVTPQLFEALVEQLADQDLVAVARQRLERKHLAVEVDV
DSL

Download         Length: 252 bp

>AT99827 NZ_CP027667:1910146-1910397 [Melaminivora sp. SC2-9]
ATGGACAACATCTACGCCGACTATTCCATCAGCATGTCCGAGTTCAAGAAGAATCCGGCCCAGGTGCTGCGCACGGCCGG
AGAAAAGCCCGTGGCCGTGCTCAATCACAACCGGCCGGCGTTCTACATGGTGACGCCACAGCTGTTCGAGGCCCTCGTCG
AGCAGCTGGCCGATCAGGATCTGGTCGCCGTGGCCCGCCAGCGCCTGGAGCGCAAGCACCTGGCCGTCGAGGTGGACGTT
GACAGCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References