Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE-PrpA/ParE-CC2985
Location 1261680..1262220 Replicon chromosome
Accession NZ_CP027667
Organism Melaminivora sp. SC2-9

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C6568_RS05955 Protein ID WP_106683331.1
Coordinates 1261930..1262220 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag C6568_RS05950 Protein ID WP_106683330.1
Coordinates 1261680..1261937 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6568_RS05930 1256947..1257492 - 546 WP_106683326.1 HAD-IIIA family hydrolase -
C6568_RS05935 1257489..1258130 - 642 WP_106683327.1 hypothetical protein -
C6568_RS05940 1258127..1260304 - 2178 WP_106683328.1 glycine--tRNA ligase subunit beta -
C6568_RS05945 1260493..1261449 - 957 WP_106683329.1 glycine--tRNA ligase subunit alpha -
C6568_RS05950 1261680..1261937 + 258 WP_106683330.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
C6568_RS05955 1261930..1262220 + 291 WP_106683331.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6568_RS05960 1262338..1263315 - 978 WP_199792803.1 hypothetical protein -
C6568_RS05965 1263450..1264856 - 1407 WP_106683332.1 dihydrolipoyl dehydrogenase -
C6568_RS05970 1264863..1266230 - 1368 WP_106683333.1 2-oxo acid dehydrogenase subunit E2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(7-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11011.39 Da        Isoelectric Point: 6.8696

>T99823 WP_106683331.1 NZ_CP027667:1261930-1262220 [Melaminivora sp. SC2-9]
MAELRLTPAALRDLETIWDYTEQRWGTAQALHYLDALETAFQSLAQAPESGQRCDAIRAGYRRSRVEQHGVYYRLEGDAV
VVVRVLHQRMDAGRHV

Download         Length: 291 bp

>T99823 NZ_CP027667:1261930-1262220 [Melaminivora sp. SC2-9]
ATGGCTGAGTTGCGCCTGACGCCAGCGGCGCTACGCGATCTGGAAACCATTTGGGATTACACCGAGCAGCGCTGGGGCAC
GGCGCAAGCGCTGCATTACCTGGATGCGCTGGAGACAGCCTTCCAGTCGCTGGCGCAGGCGCCGGAATCCGGCCAGCGCT
GCGATGCCATTCGCGCCGGCTATCGCCGCAGCCGGGTGGAGCAGCACGGTGTGTATTACCGCCTGGAAGGCGACGCAGTA
GTTGTGGTGCGGGTACTGCACCAGCGTATGGATGCTGGCCGCCACGTGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9546.74 Da        Isoelectric Point: 8.7087

>AT99823 WP_106683330.1 NZ_CP027667:1261680-1261937 [Melaminivora sp. SC2-9]
MSTVRKTITLTDTQDGWVKAQIEAGHYTNDSEVIRALIRREQERMSELQALRSALLQGENSGEPQPFDAQAFRARMLAKR
SVANG

Download         Length: 258 bp

>AT99823 NZ_CP027667:1261680-1261937 [Melaminivora sp. SC2-9]
ATGTCCACGGTGCGCAAAACCATCACTCTTACCGACACCCAGGATGGCTGGGTAAAGGCACAGATCGAGGCAGGGCATTA
CACCAACGACAGCGAAGTGATCCGCGCGCTGATCCGCCGCGAGCAGGAACGCATGTCGGAGTTGCAGGCACTGCGCTCGG
CCTTGCTGCAGGGCGAAAACAGTGGCGAACCTCAGCCATTTGACGCGCAGGCGTTCCGAGCTCGCATGCTGGCAAAGCGA
TCGGTTGCAAATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References