Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2266556..2267226 Replicon chromosome
Accession NZ_CP027666
Organism Ottowia oryzae strain KADR8-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C6570_RS10515 Protein ID WP_106703157.1
Coordinates 2266556..2266972 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C6570_RS10520 Protein ID WP_106703158.1
Coordinates 2266969..2267226 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6570_RS10495 2262646..2262990 - 345 WP_106704643.1 hypothetical protein -
C6570_RS10500 2263336..2263740 - 405 WP_106703155.1 phage holin family protein -
C6570_RS10505 2263926..2264705 - 780 WP_106704644.1 hypothetical protein -
C6570_RS10510 2265031..2266185 + 1155 WP_164675528.1 Fic family protein -
C6570_RS18155 2266296..2266433 - 138 WP_164675529.1 hypothetical protein -
C6570_RS10515 2266556..2266972 - 417 WP_106703157.1 type II toxin-antitoxin system VapC family toxin Toxin
C6570_RS10520 2266969..2267226 - 258 WP_106703158.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6570_RS10525 2267251..2267499 + 249 WP_123812248.1 hypothetical protein -
C6570_RS10530 2268032..2268466 + 435 WP_106703160.1 CopG family transcriptional regulator -
C6570_RS10535 2268510..2269703 + 1194 WP_106703161.1 PHB depolymerase family esterase -
C6570_RS10540 2269808..2270404 + 597 WP_106703162.1 Fic family protein -
C6570_RS18000 2270655..2271569 - 915 WP_123812249.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2265031..2273660 8629


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-61)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15078.45 Da        Isoelectric Point: 8.5840

>T99820 WP_106703157.1 NZ_CP027666:c2266972-2266556 [Ottowia oryzae]
MSYLIDTNALSELRRKAPDANVVAWFAQRPPVTLYLSVLTLGEIRKGVEGAADTARRQALTDWLETDLPLFFTGRILVVD
GAVADRWGRLVAAAGRPLPAIDSLLAATALAHDLVLVTRNTKDFAGLPVQVFNPWLKN

Download         Length: 417 bp

>T99820 NZ_CP027666:c2266972-2266556 [Ottowia oryzae]
TTGAGCTACCTCATCGACACCAACGCGCTGTCCGAACTGCGCCGCAAGGCACCCGATGCCAACGTGGTCGCCTGGTTTGC
CCAGCGGCCGCCGGTGACGCTGTACCTGAGCGTGCTGACGCTGGGCGAAATCCGCAAAGGCGTGGAAGGCGCCGCCGACA
CAGCGCGCCGGCAGGCGCTCACGGACTGGCTGGAGACCGATTTGCCGCTGTTCTTTACCGGCCGCATCCTGGTTGTGGAT
GGCGCTGTCGCAGACCGTTGGGGCCGTCTGGTGGCGGCGGCCGGCCGGCCTCTGCCTGCGATTGACAGCCTGCTGGCCGC
CACGGCACTGGCGCACGACCTGGTGCTGGTCACGCGCAACACCAAGGACTTTGCGGGGCTGCCCGTGCAGGTGTTCAACC
CCTGGTTGAAGAACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9635.76 Da        Isoelectric Point: 4.7223

>AT99820 WP_106703158.1 NZ_CP027666:c2267226-2266969 [Ottowia oryzae]
MQTWQMQDAKARMSELVKSAQTQPQDITVHGKSVAVVVSRSTFDRLSQAQGSLVDFMRRSPLFDADDVVFERDTSLTRQP
EDEGF

Download         Length: 258 bp

>AT99820 NZ_CP027666:c2267226-2266969 [Ottowia oryzae]
ATGCAAACATGGCAAATGCAAGACGCCAAGGCGCGCATGTCGGAGCTGGTCAAGTCGGCGCAGACGCAGCCGCAAGACAT
CACGGTGCATGGCAAGTCGGTGGCAGTGGTGGTGTCGCGCAGCACCTTTGACCGCCTGTCGCAGGCGCAGGGCTCGCTGG
TGGATTTCATGCGGCGCTCACCGCTCTTTGACGCCGATGACGTGGTGTTTGAACGCGATACCAGCCTCACGCGCCAGCCA
GAGGACGAGGGCTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References