Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA(toxin)
Location 3078064..3079691 Replicon chromosome
Accession NZ_CP027663
Organism Acidiferrobacter sp. SPIII_3

Toxin (Protein)


Gene name HipA3 Uniprot ID -
Locus tag C4901_RS15695 Protein ID WP_110138133.1
Coordinates 3078387..3079691 (+) Length 435 a.a.

Antitoxin (Protein)


Gene name HipB3 Uniprot ID -
Locus tag C4901_RS15690 Protein ID WP_168185772.1
Coordinates 3078064..3078393 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4901_RS15680 3073064..3076708 + 3645 WP_110138131.1 AAA family ATPase -
C4901_RS18295 3076922..3077806 - 885 WP_205736073.1 SEC-C domain-containing protein -
C4901_RS15690 3078064..3078393 + 330 WP_168185772.1 helix-turn-helix transcriptional regulator Antitoxin
C4901_RS15695 3078387..3079691 + 1305 WP_110138133.1 type II toxin-antitoxin system HipA family toxin Toxin
C4901_RS15700 3079791..3081446 + 1656 WP_205736074.1 peptide ABC transporter substrate-binding protein -
C4901_RS15705 3081499..3082446 + 948 WP_110138134.1 ABC transporter permease -
C4901_RS15710 3082439..3083332 + 894 WP_110138135.1 ABC transporter permease -
C4901_RS15715 3083329..3084306 + 978 WP_110138136.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(11-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 435 a.a.        Molecular weight: 48216.18 Da        Isoelectric Point: 8.9459

>T99817 WP_110138133.1 NZ_CP027663:3078387-3079691 [Acidiferrobacter sp. SPIII_3]
MVTRTTTAIARLWGQDIGAVSWLPDRELAAFEFEPRFLALGLDVAPLVMPRARARGQVFVFPTLNRETFMGLPGLLADAL
PDKFGNALIDAWLARTGRVIAEFNPVERLCYMGDRGMGALEFRPALNTDLKRRVSVDIAELVALAREVTAARDRLDARVG
SGDGPDAEALRDILRVGTSAGGARAKAVIAMNGAGRILSGQGPVPEGYDHWLLKFDGVADLELGKTRDHGRIEYAYSLMA
SAAGITMSECRLLEENGRAHFLTKRFDRGTLGKRHLQSLCGLAHYDYNAPGAYGYEQVFAVMRELRLPRAEAVQQYRRML
FNVVARNQDDHTKNIAFLMDQDGQWRLAPAFDMIYAHNPGGRWTSRHQMTINGKRDGFTRDDLLAVGRSLGIHAPDRMLG
EIVDVVARWPDYARETGVNPARAREILSTLRLAW

Download         Length: 1305 bp

>T99817 NZ_CP027663:3078387-3079691 [Acidiferrobacter sp. SPIII_3]
ATGGTAACGCGCACGACGACCGCGATCGCACGGCTCTGGGGACAGGACATAGGGGCGGTCAGCTGGCTACCGGACCGGGA
GCTGGCGGCCTTCGAATTCGAACCGCGATTCCTGGCCTTGGGTCTCGACGTCGCACCACTTGTCATGCCGCGTGCTCGGG
CGCGCGGGCAGGTGTTCGTCTTCCCGACCTTGAACCGCGAGACCTTCATGGGCCTGCCGGGCCTTTTGGCCGACGCCCTG
CCCGACAAGTTCGGCAACGCCTTGATAGACGCCTGGCTGGCCCGCACCGGTCGCGTAATCGCCGAGTTCAACCCGGTGGA
GCGCCTCTGTTATATGGGCGACCGCGGCATGGGCGCCCTCGAATTCCGCCCGGCCCTCAACACCGACCTCAAGCGCCGCG
TATCCGTCGACATCGCCGAACTCGTCGCACTGGCCCGCGAGGTGACCGCCGCCCGAGACCGTCTCGATGCCCGTGTCGGT
AGTGGCGACGGCCCGGACGCCGAGGCCTTGCGCGACATCCTGCGCGTGGGTACCTCGGCGGGCGGGGCACGCGCCAAGGC
GGTCATCGCCATGAATGGCGCCGGCCGGATCCTGTCCGGCCAGGGACCGGTGCCCGAGGGCTATGATCACTGGCTCCTCA
AGTTCGACGGCGTGGCCGATCTCGAGCTTGGCAAGACCCGGGACCACGGGCGTATCGAATACGCCTACTCGCTCATGGCC
TCGGCCGCGGGGATCACGATGAGCGAGTGTCGTCTTCTGGAAGAAAACGGCCGGGCCCACTTCCTCACGAAACGCTTCGA
TCGCGGGACCCTGGGCAAACGCCATCTGCAATCGCTCTGCGGGCTTGCACATTACGACTACAACGCCCCCGGGGCCTATG
GATATGAGCAGGTGTTCGCGGTCATGCGCGAGTTGCGCCTGCCGCGCGCGGAGGCCGTTCAACAATACCGGCGCATGCTG
TTCAATGTCGTGGCCCGCAACCAGGACGACCACACCAAAAACATTGCATTCCTGATGGATCAGGACGGCCAATGGCGGCT
CGCCCCCGCCTTCGACATGATATACGCCCACAACCCGGGCGGCCGCTGGACCAGCCGTCACCAGATGACCATCAACGGAA
AACGCGACGGCTTTACGCGCGACGATCTGCTGGCCGTGGGGCGGTCCCTGGGTATCCACGCACCGGATCGGATGCTGGGG
GAGATCGTCGATGTCGTGGCGCGGTGGCCCGACTACGCGCGCGAGACCGGCGTCAATCCCGCCCGCGCCCGCGAGATCCT
GAGCACCCTGCGGCTCGCGTGGTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11493.27 Da        Isoelectric Point: 12.0123

>AT99817 WP_168185772.1 NZ_CP027663:3078064-3078393 [Acidiferrobacter sp. SPIII_3]
MDTGHESLSDRAIAARLGERLRALRLRRNRTQEDVAARAAVSLGTLKALEAGRGKLETLIAILRELGALAAVDALLPEPP
VSPLALARRGRGRRRASAKGGAGPDGPAW

Download         Length: 330 bp

>AT99817 NZ_CP027663:3078064-3078393 [Acidiferrobacter sp. SPIII_3]
ATGGACACCGGACATGAATCGCTCAGTGACCGCGCCATCGCCGCGCGGCTCGGGGAGCGGCTACGCGCCTTGCGGTTACG
CCGCAACCGCACCCAAGAAGACGTGGCCGCCCGTGCCGCCGTGAGTCTCGGGACCTTGAAGGCCCTGGAGGCCGGGCGCG
GCAAGCTCGAGACCCTGATCGCGATCTTGCGGGAACTGGGCGCGCTGGCCGCCGTCGACGCCCTTCTCCCCGAACCACCG
GTAAGTCCGCTGGCGCTCGCCCGCCGGGGGCGGGGGCGCCGTCGGGCCTCGGCTAAGGGCGGGGCGGGTCCAGATGGGCC
CGCATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References