99813

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1519654..1520282 Replicon chromosome
Accession NZ_CP027663
Organism Acidiferrobacter sp. SPIII_3

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag C4901_RS07625 Protein ID WP_110136816.1
Coordinates 1519980..1520282 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag C4901_RS07620 Protein ID WP_110136815.1
Coordinates 1519654..1519983 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4901_RS07595 1515773..1516390 - 618 WP_110136812.1 transposase -
C4901_RS07600 1516272..1516754 - 483 WP_145960662.1 transposase -
C4901_RS07605 1516897..1518248 + 1352 Protein_1499 ISNCY family transposase -
C4901_RS07610 1518303..1518497 + 195 WP_110135574.1 DUF4338 domain-containing protein -
C4901_RS07615 1518863..1519357 + 495 WP_145960663.1 hypothetical protein -
C4901_RS07620 1519654..1519983 - 330 WP_110136815.1 helix-turn-helix domain-containing protein Antitoxin
C4901_RS07625 1519980..1520282 - 303 WP_110136816.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4901_RS07630 1520479..1520727 - 249 WP_145960664.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
C4901_RS07635 1521246..1521386 + 141 Protein_1505 transposase -
C4901_RS17640 1521890..1522051 - 162 WP_168185624.1 hypothetical protein -
C4901_RS07640 1522198..1522707 - 510 WP_110136818.1 peptidylprolyl isomerase -
C4901_RS07645 1522723..1523112 - 390 WP_110136819.1 hypothetical protein -
C4901_RS07650 1523204..1525072 - 1869 WP_110136820.1 adenylyl-sulfate reductase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-88)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11146.57 Da        Isoelectric Point: 6.9781

>T99813 WP_110136816.1 NZ_CP027663:c1520282-1519980 [Acidiferrobacter sp. SPIII_3]
MPEEVQDTFGYALYLAQIGGKHEQAKALKGFGSADVQEIVERSEGGSFRAVYTVRFAEAIYVLHCFQKKSTHGIATPKPD
IDKIHERLRIAEQHAKGENS

Download         Length: 303 bp

>T99813 NZ_CP027663:c1520282-1519980 [Acidiferrobacter sp. SPIII_3]
ATGCCGGAAGAGGTGCAGGACACCTTTGGGTACGCGCTGTACTTGGCGCAGATTGGAGGGAAGCACGAACAGGCCAAAGC
GCTCAAAGGCTTCGGATCGGCGGATGTCCAGGAGATTGTGGAGCGGTCGGAGGGCGGCTCGTTTCGGGCGGTCTATACCG
TGCGATTCGCCGAGGCTATCTATGTGCTGCATTGTTTCCAGAAGAAATCGACGCACGGGATCGCCACGCCCAAGCCCGAC
ATTGACAAGATTCACGAGCGGTTGCGCATTGCCGAACAGCACGCGAAAGGAGAGAACTCATGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12020.99 Da        Isoelectric Point: 9.8634

>AT99813 WP_110136815.1 NZ_CP027663:c1519983-1519654 [Acidiferrobacter sp. SPIII_3]
MKTVEPSSGNVYEDLGRPDAEEMMMKAQLAVKIGEIITERQWSQQHAATILGLTQPKLSQMLRGQFRGISETKMLDGLAR
LGLDVQIIIGPARPTPNAHHKRVGIVFTA

Download         Length: 330 bp

>AT99813 NZ_CP027663:c1519983-1519654 [Acidiferrobacter sp. SPIII_3]
ATGAAGACCGTCGAACCGAGCAGTGGGAACGTCTACGAAGACCTGGGTCGCCCGGATGCGGAAGAGATGATGATGAAAGC
CCAGCTCGCCGTCAAGATTGGCGAGATTATCACGGAACGGCAATGGAGCCAACAGCATGCGGCGACCATTCTTGGCCTCA
CTCAGCCCAAGCTCTCGCAGATGCTGCGCGGTCAGTTCCGCGGCATAAGCGAGACGAAGATGCTGGATGGGCTGGCACGG
CTGGGGCTTGATGTGCAAATCATTATTGGACCCGCGCGACCCACCCCCAACGCGCACCACAAACGCGTGGGAATCGTCTT
CACGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References