Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1373677..1374230 Replicon chromosome
Accession NZ_CP027663
Organism Acidiferrobacter sp. SPIII_3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4901_RS06885 Protein ID WP_110136691.1
Coordinates 1373677..1373970 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4901_RS06890 Protein ID WP_110136692.1
Coordinates 1373958..1374230 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4901_RS06865 1369030..1369674 + 645 WP_110136688.1 response regulator -
C4901_RS06870 1369952..1370977 - 1026 WP_168185602.1 metallophosphoesterase -
C4901_RS06875 1371176..1371445 + 270 WP_110136690.1 hypothetical protein -
C4901_RS06880 1371762..1372976 - 1215 WP_205736247.1 Fic family protein -
C4901_RS17595 1373391..1373567 + 177 WP_168185603.1 hypothetical protein -
C4901_RS06885 1373677..1373970 - 294 WP_110136691.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4901_RS06890 1373958..1374230 - 273 WP_110136692.1 CopG family ribbon-helix-helix protein Antitoxin
C4901_RS06895 1374384..1374509 - 126 WP_110136693.1 transposase -
C4901_RS06900 1374506..1375510 - 1005 WP_168185604.1 ISL3 family transposase -
C4901_RS06905 1376373..1376717 + 345 WP_110136695.1 toxin -
C4901_RS06910 1376714..1377037 + 324 WP_110136696.1 transcriptional regulator -
C4901_RS06915 1377100..1377474 - 375 WP_145960642.1 hypothetical protein -
C4901_RS06920 1377704..1378228 - 525 WP_110136698.1 GNAT family N-acetyltransferase -
C4901_RS06925 1378236..1378511 - 276 WP_110136699.1 DUF1778 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10770.31 Da        Isoelectric Point: 6.4654

>T99809 WP_110136691.1 NZ_CP027663:c1373970-1373677 [Acidiferrobacter sp. SPIII_3]
VPRVVITEGAAEGLERCRRFLADKAPEAATRAGQAIAQQFRLLETAPGMGRPLPEMPELRELVVAFGDSGYVALYRHDPT
KDEVYVLAFRHQKEAGY

Download         Length: 294 bp

>T99809 NZ_CP027663:c1373970-1373677 [Acidiferrobacter sp. SPIII_3]
GTGCCACGAGTAGTCATCACGGAAGGCGCAGCGGAAGGCTTGGAGCGATGCCGGAGATTCTTGGCCGACAAAGCCCCCGA
AGCCGCCACGCGGGCCGGTCAGGCGATCGCCCAACAATTTCGGCTGCTGGAAACCGCCCCCGGCATGGGTCGTCCGCTCC
CGGAAATGCCTGAGCTGCGCGAGCTGGTGGTCGCCTTCGGAGACTCCGGCTATGTGGCCTTGTACCGCCATGATCCGACC
AAAGACGAGGTGTACGTTCTTGCCTTTCGCCACCAAAAAGAGGCGGGCTACTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10484.62 Da        Isoelectric Point: 4.9049

>AT99809 WP_110136692.1 NZ_CP027663:c1374230-1373958 [Acidiferrobacter sp. SPIII_3]
MATSLKIDDALKSRIQQLAGQRRRSPHWIMLEAIQQYVEREEARESFRQEALASWAAYQETGRHLTGEDVRAWLDTWGTD
DEKGVPECHE

Download         Length: 273 bp

>AT99809 NZ_CP027663:c1374230-1373958 [Acidiferrobacter sp. SPIII_3]
ATGGCAACATCCCTCAAGATCGACGACGCACTGAAAAGCCGCATCCAGCAGCTCGCCGGTCAGCGCCGCCGCTCGCCGCA
TTGGATAATGCTGGAGGCCATTCAACAGTACGTCGAGCGCGAAGAGGCGCGTGAGAGCTTCAGGCAGGAGGCCTTGGCGT
CCTGGGCGGCTTATCAGGAAACCGGACGGCATCTGACCGGCGAAGACGTTCGTGCTTGGTTAGATACCTGGGGCACCGAT
GATGAAAAAGGCGTTCCTGAGTGCCACGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References