Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 824519..825936 Replicon chromosome
Accession NZ_CP027657
Organism Pseudomonas mendocina strain NEB698

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag C7A17_RS03890 Protein ID WP_106736781.1
Coordinates 825367..825936 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag C7A17_RS03885 Protein ID WP_106736780.1
Coordinates 824519..825361 (-) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7A17_RS03870 821381..822286 - 906 WP_106736777.1 hypothetical protein -
C7A17_RS03875 822288..822860 - 573 WP_106736778.1 LemA family protein -
C7A17_RS03880 823051..824388 + 1338 WP_106736779.1 peptidase -
C7A17_RS03885 824519..825361 - 843 WP_106736780.1 AraC family transcriptional regulator Antitoxin
C7A17_RS03890 825367..825936 - 570 WP_106736781.1 GNAT family N-acetyltransferase Toxin
C7A17_RS03895 826138..829626 + 3489 WP_106736782.1 hybrid sensor histidine kinase/response regulator -
C7A17_RS03900 829702..830514 - 813 WP_106736783.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-269)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21493.70 Da        Isoelectric Point: 9.5184

>T99803 WP_106736781.1 NZ_CP027657:c825936-825367 [Pseudomonas mendocina]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANREELLYMSGTQRLDWYRSALADLREQRALPFVIRLGDVLVGTTRFA
DFMNTLPACEIGWTWLDRSQHGSGLNTSIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDQQWPQVREALESRFGA

Download         Length: 570 bp

>T99803 NZ_CP027657:c825936-825367 [Pseudomonas mendocina]
ATGTTCAAGCCGCAACTGGTCACGCTGCAACGTGGTGCTTTACGCCTGGAACCGCTGGCCGATGCCGATATTCCTGCATT
GGTGGCGCTGGCCGAGGCCAATCGCGAAGAGCTGCTTTACATGAGTGGTACTCAGCGTCTGGATTGGTATCGCAGCGCGC
TGGCCGATCTGCGCGAGCAGCGCGCACTGCCGTTCGTCATCCGGCTCGGCGACGTGCTGGTGGGGACGACTCGTTTCGCT
GATTTCATGAACACGCTGCCGGCCTGTGAAATTGGCTGGACCTGGCTCGATCGCAGCCAGCATGGCAGTGGGCTGAACAC
CAGCATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACTGGGGCATGGTGCGCGTGCAACTGAAGACCGCAGCCAGCA
ACCTGCGCTCGCAGCGCGCCATCGAAAAGCTCGGTGCCGTGCGTGAAGGGCTGCTGCGCAATCATCGTCGCCTGGCCGAT
GGACGTCTCGACGACACCGTGCTGTACAGCATCACCGATCAGCAATGGCCGCAGGTGCGCGAAGCACTGGAGTCGCGCTT
CGGCGCCTGA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31180.47 Da        Isoelectric Point: 8.7342

>AT99803 WP_106736780.1 NZ_CP027657:c825361-824519 [Pseudomonas mendocina]
MASREHTRFWQASALSGVELLQARYREQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPSNGQVLGALQELGLASAGMPSFDSSVLHDPQLHAAFLHLHRLLEDGAEALQQQLAWREAILALFQRHARI
AEPPLPGREPWAVSCAKQMLAERLVEPPSLEELASAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKGGCSAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSGVARVVVGDS

Download         Length: 843 bp

>AT99803 NZ_CP027657:c825361-824519 [Pseudomonas mendocina]
ATGGCGAGTCGCGAGCACACACGTTTCTGGCAGGCCTCGGCGTTATCCGGGGTAGAACTGTTACAGGCGCGTTATCGCGA
GCAACGCTTCGCACCTCATGTGCACGAGGGCTTCGTCTTCACCGTGATCGAACACGGCGCCCAGCGCTTTCGCCATCGCG
GCTGCGATCATTTGGCGCCGCAGGGCAGCATGGTGCTGATCAACCCGGATGAGGTACATACCGGTTCCAAGGCTCATGAA
GATGGTTGGCGTTACCGGGGGTTCTACCCCAGCAACGGCCAGGTACTGGGTGCATTGCAGGAACTCGGTCTGGCCAGCGC
CGGCATGCCGTCATTCGACTCCAGCGTGCTGCATGACCCGCAGCTGCATGCGGCCTTTCTGCATCTGCATCGCCTGCTCG
AGGATGGTGCTGAGGCATTGCAGCAGCAACTGGCCTGGCGCGAAGCCATTCTGGCGTTGTTCCAGCGTCATGCGCGAATA
GCCGAGCCACCGTTGCCCGGCCGCGAGCCCTGGGCCGTTTCGTGCGCCAAGCAGATGCTCGCCGAAAGACTGGTCGAGCC
ACCCTCGCTGGAAGAGTTGGCGAGTGCAGTCAATCTGTCGCCCTTTCACTTCGCCCGGGTTTTTCGTCGCGCCACTGGCC
TGCCTCCGCATGCCTGGCTCAAACAGCGACGCCTGGAGCAGGCGCGTGCCTTGCTCAAAGGCGGTTGCTCGGCAGTCGCG
GTCGCCATGCAGCTGGGTTTTGCCGATCAGAGTCATCTGTCACGGCAGTTCAAGCAGGTCTATGGCGTCAGCCCTGGCGA
ATACCGCAGCGGCGTAGCGCGGGTTGTGGTTGGGGATTCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References