Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966473..1966744 Replicon chromosome
Accession NZ_CP027591
Organism Escherichia coli strain 2014C-3011

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966603..1966706 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966473..1966744 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7A05_RS11695 1963028..1963690 - 663 WP_000944256.1 exodeoxyribonuclease X -
C7A05_RS11700 1963714..1964370 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
C7A05_RS11705 1964472..1964702 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C7A05_RS11710 1964841..1965215 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C7A05_RS11715 1965219..1966091 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C7A05_RS11720 1966104..1966445 + 342 WP_000976472.1 YebY family protein -
- 1966473..1966744 - 272 - - Antitoxin
- 1966603..1966706 + 104 - - Toxin
C7A05_RS11725 1966841..1967497 + 657 WP_000812722.1 protein-serine/threonine phosphatase -
C7A05_RS11730 1967498..1967689 - 192 WP_001296140.1 YebW family protein -
C7A05_RS11735 1967794..1968030 - 237 WP_001295499.1 DUF1480 family protein -
C7A05_RS11740 1968148..1969587 - 1440 WP_024226338.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99686 NZ_CP027591:1966603-1966706 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT99686 NZ_CP027591:c1966744-1966473 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References