Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1283243..1283514 Replicon chromosome
Accession NZ_CP027587
Organism Escherichia coli strain 2013C-4974

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1283373..1283476 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1283243..1283514 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6998_RS07075 1279798..1280460 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6998_RS07080 1280484..1281140 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
C6998_RS07085 1281242..1281472 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6998_RS07090 1281611..1281985 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C6998_RS07095 1281989..1282861 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6998_RS07100 1282874..1283215 + 342 WP_097453198.1 YebY family protein -
- 1283243..1283514 - 272 - - Antitoxin
- 1283373..1283476 + 104 - - Toxin
C6998_RS07105 1283611..1284267 + 657 WP_000812722.1 protein-serine/threonine phosphatase -
C6998_RS07110 1284268..1284459 - 192 WP_001296140.1 YebW family protein -
C6998_RS07115 1284564..1284800 - 237 WP_001295499.1 DUF1480 family protein -
C6998_RS07120 1284918..1286357 - 1440 WP_106878525.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99650 NZ_CP027587:1283373-1283476 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT99650 NZ_CP027587:c1283514-1283243 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References