Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 971762..971996 Replicon chromosome
Accession NZ_CP027582
Organism Escherichia coli strain 2013C-4538

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 971892..971995 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 971762..971996 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6999_RS05035 968317..968979 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6999_RS05040 969003..969659 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6999_RS05045 969761..969991 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6999_RS05050 970130..970504 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C6999_RS05055 970508..971380 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6999_RS05060 971393..971734 + 342 WP_000976492.1 YebY family protein -
- 971762..971996 - 235 - - Antitoxin
- 971892..971995 + 104 - - Toxin
C6999_RS05065 972127..973203 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
C6999_RS05070 973169..973450 - 282 WP_001443927.1 excisionase -
C6999_RS05075 973557..973745 - 189 WP_001356607.1 DUF1187 family protein -
- 973561..973739 + 179 NuclAT_1 - -
- 973561..973739 + 179 NuclAT_1 - -
- 973561..973739 + 179 NuclAT_1 - -
- 973561..973739 + 179 NuclAT_1 - -
C6999_RS05080 973738..973932 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
C6999_RS05085 973989..974798 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 964352..1034677 70325


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99568 NZ_CP027582:971892-971995 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT99568 NZ_CP027582:c971996-971762 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References