Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 633275..633543 Replicon chromosome
Accession NZ_CP027579
Organism Escherichia coli strain 2013C-4282

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 633402..633505 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 633275..633543 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6996_RS03110 629828..630490 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6996_RS03115 630514..631170 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
C6996_RS03120 631272..631502 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6996_RS03125 631641..632015 + 375 WP_000204701.1 CopC domain-containing protein YobA -
C6996_RS03130 632019..632891 + 873 WP_000879324.1 copper homeostasis membrane protein CopD -
C6996_RS03135 632904..633245 + 342 WP_000976467.1 YebY family protein -
- 633275..633543 - 269 - - Antitoxin
- 633402..633505 + 104 - - Toxin
C6996_RS03140 633640..634296 + 657 WP_105276934.1 protein-serine/threonine phosphatase -
C6996_RS03145 634297..634488 - 192 WP_001296140.1 YebW family protein -
C6996_RS03150 634593..634829 - 237 WP_001295499.1 DUF1480 family protein -
C6996_RS03155 634947..636386 - 1440 WP_105267346.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T99537 NZ_CP027579:633402-633505 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT99537 NZ_CP027579:c633543-633275 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References