Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3988549..3988783 | Replicon | chromosome |
| Accession | NZ_CP027577 | ||
| Organism | Escherichia coli strain 2013C-4225 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3988550..3988653 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3988549..3988783 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6997_RS21890 | 3985747..3986556 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| C6997_RS21895 | 3986613..3986807 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C6997_RS21900 | 3986800..3986988 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 3986806..3986984 | - | 179 | NuclAT_1 | - | - |
| - | 3986806..3986984 | - | 179 | NuclAT_1 | - | - |
| - | 3986806..3986984 | - | 179 | NuclAT_1 | - | - |
| - | 3986806..3986984 | - | 179 | NuclAT_1 | - | - |
| C6997_RS21905 | 3987095..3987376 | + | 282 | WP_001443927.1 | excisionase | - |
| C6997_RS21910 | 3987342..3988418 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3988549..3988783 | + | 235 | - | - | Antitoxin |
| - | 3988550..3988653 | - | 104 | - | - | Toxin |
| C6997_RS21915 | 3988811..3989152 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C6997_RS21920 | 3989165..3990037 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| C6997_RS21925 | 3990041..3990415 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C6997_RS21930 | 3990554..3990784 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C6997_RS21935 | 3990886..3991542 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C6997_RS21940 | 3991566..3992228 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 3917494..3996193 | 78699 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T99523 NZ_CP027577:c3988653-3988550 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT99523 NZ_CP027577:3988549-3988783 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
