Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 297047..297695 Replicon chromosome
Accession NZ_CP027562
Organism Stenotrophomonas maltophilia strain SJTH1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C6Y55_RS01305 Protein ID WP_097048217.1
Coordinates 297047..297334 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C6Y55_RS01310 Protein ID WP_106466784.1
Coordinates 297393..297695 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6Y55_RS01275 292307..293275 + 969 WP_094001616.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
C6Y55_RS01280 293272..294003 + 732 WP_049435511.1 type III pantothenate kinase -
C6Y55_RS01285 294013..294861 + 849 WP_106466781.1 SPOR domain-containing protein -
C6Y55_RS01295 295062..296186 - 1125 WP_106466782.1 hypothetical protein -
C6Y55_RS01300 296214..296813 - 600 WP_158704737.1 hypothetical protein -
C6Y55_RS01305 297047..297334 + 288 WP_097048217.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6Y55_RS01310 297393..297695 + 303 WP_106466784.1 putative addiction module antidote protein Antitoxin
C6Y55_RS01315 297801..298094 - 294 WP_106466785.1 hypothetical protein -
C6Y55_RS01320 298153..298557 - 405 WP_106466786.1 hypothetical protein -
C6Y55_RS01325 299154..299918 + 765 WP_106466787.1 DUF3011 domain-containing protein -
C6Y55_RS01330 300045..300569 - 525 WP_158704738.1 hypothetical protein -
C6Y55_RS01335 300608..301483 - 876 WP_106466789.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10716.33 Da        Isoelectric Point: 10.7813

>T99470 WP_097048217.1 NZ_CP027562:297047-297334 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARAL

Download         Length: 288 bp

>T99470 NZ_CP027562:297047-297334 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGCACGCGCTCGCATCCTGGC
CCGTATCGGTCGGCTCGCTGAAGGCCATCCCGGTGATCACCGCTATCTGGCGGATGGCGTTTCTGAATTGCGTATCGATG
CAGGACCGGGTTACCGCGTTTACTACACCCAGCGCGGCAGGCAGTTGGTGATTCTCCTGGTTGGAGGCGACAAAGGTTCG
CAGCAGCGCGATATCGAGAAGGCCAAGGAGATTGCGCGTGCCCTGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10806.44 Da        Isoelectric Point: 8.0359

>AT99470 WP_106466784.1 NZ_CP027562:297393-297695 [Stenotrophomonas maltophilia]
MVIKRKVELKSFDVAEHLRTPEEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAV

Download         Length: 303 bp

>AT99470 NZ_CP027562:297393-297695 [Stenotrophomonas maltophilia]
ATGGTCATCAAGAGAAAAGTCGAACTCAAATCATTTGATGTGGCCGAGCATCTTCGGACGCCGGAGGAGATGGCGGCTTA
TCTCGACGCCTGCATCGAAGAGAGCGACGGTGATTCTGCCTTCATCGCCAAGGCGCTCGGCGATATCGCCCGCGCTCAGG
GGATGAGCAAGGTTGCGCGTGCGGCGGGTTTGTCGCGCGAGAGTCTCTACCGCGCACTGTCCGGCGAGCGCAGCCCCGAT
TTCGCCACCATCCTGAAGGTGACCCGTGCCCTGGGTGTGCGATTGCATGCCAGCGCTGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References