Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1789272..1790311 Replicon chromosome
Accession NZ_CP027561
Organism Pseudomonas fluorescens strain G7

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C6Y56_RS08055 Protein ID WP_108560305.1
Coordinates 1789272..1789847 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C6Y56_RS08060 Protein ID WP_169429431.1
Coordinates 1789844..1790311 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6Y56_RS08030 1784604..1786592 + 1989 WP_169429427.1 heme lyase CcmF/NrfE family subunit -
C6Y56_RS08035 1786589..1787125 + 537 WP_011333088.1 DsbE family thiol:disulfide interchange protein -
C6Y56_RS08040 1787122..1787592 + 471 WP_169429428.1 cytochrome c-type biogenesis protein CcmH -
C6Y56_RS08045 1787589..1788788 + 1200 WP_169429429.1 c-type cytochrome biogenesis protein CcmI -
C6Y56_RS08050 1788814..1789221 + 408 WP_169429430.1 hypothetical protein -
C6Y56_RS08055 1789272..1789847 - 576 WP_108560305.1 PIN domain-containing protein Toxin
C6Y56_RS08060 1789844..1790311 - 468 WP_169429431.1 helix-turn-helix domain-containing protein Antitoxin
C6Y56_RS08065 1790591..1790995 + 405 WP_085666700.1 type II toxin-antitoxin system HicB family antitoxin -
C6Y56_RS08070 1791044..1792231 - 1188 WP_169429432.1 MFS transporter -
C6Y56_RS08075 1792475..1793095 + 621 WP_169429433.1 hypothetical protein -
C6Y56_RS08080 1793151..1794149 - 999 WP_169429434.1 sulfate ABC transporter substrate-binding protein -
C6Y56_RS08085 1794255..1795079 - 825 WP_064378643.1 ion transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21519.80 Da        Isoelectric Point: 5.9178

>T99465 WP_108560305.1 NZ_CP027561:c1789847-1789272 [Pseudomonas fluorescens]
VRHSSFTALYDACVLYPAPLRDFLMWLALSGRFRARWTQEIHCEWKRNLLKNRPDLTMEQLDRTSGLMDQAIPDACVHDY
EDLIAGLSLPDCDDRHVLAAAIRCGASVIVTFNQKDFPCKALEPFGIEAQHPDEFVDNLLGLDAAAVVAAAQKQRRQLKM
PAMDVEPFLDLLQRQGLIKSVQALSSYHAIL

Download         Length: 576 bp

>T99465 NZ_CP027561:c1789847-1789272 [Pseudomonas fluorescens]
GTGAGGCATTCCTCTTTCACCGCTTTATATGATGCATGCGTCTTGTACCCCGCCCCCTTGAGAGACTTCCTCATGTGGCT
TGCCCTCTCGGGGCGATTTCGGGCGCGATGGACCCAGGAGATTCACTGCGAATGGAAACGCAATCTGCTGAAGAACCGCC
CTGACCTGACGATGGAACAGCTGGATCGTACGTCCGGCCTGATGGATCAAGCGATACCCGACGCCTGTGTCCATGACTAT
GAAGACCTGATTGCCGGACTCAGCTTGCCCGACTGCGATGATCGTCATGTTCTGGCAGCGGCCATCCGTTGCGGCGCAAG
CGTGATAGTGACGTTCAACCAGAAAGACTTTCCCTGCAAAGCGCTGGAGCCTTTCGGCATCGAAGCGCAGCATCCGGACG
AGTTCGTCGACAACCTCTTGGGGCTTGATGCGGCAGCAGTGGTTGCAGCGGCCCAAAAACAGCGTCGGCAGCTGAAAATG
CCTGCCATGGACGTCGAACCCTTTCTTGATCTACTGCAACGACAAGGCCTGATTAAATCGGTCCAGGCACTCAGCAGTTA
TCACGCGATCCTTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17233.68 Da        Isoelectric Point: 6.2909

>AT99465 WP_169429431.1 NZ_CP027561:c1790311-1789844 [Pseudomonas fluorescens]
MSTVIHPSISLPVECEIKAAIEGQRALAAYLATHFETQHIQIFDEQNEAHRVELPTSALRLLIEILAELAAGNAVQVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKTRRTSASEQAMALLAEQAQALRTGYE

Download         Length: 468 bp

>AT99465 NZ_CP027561:c1790311-1789844 [Pseudomonas fluorescens]
ATGTCGACCGTTATTCATCCCTCCATCAGCCTCCCCGTAGAATGCGAAATAAAAGCCGCCATTGAAGGGCAGCGTGCCCT
GGCCGCTTACCTTGCGACCCATTTCGAGACCCAGCACATTCAGATTTTCGACGAGCAGAATGAAGCTCATCGCGTTGAAC
TGCCCACCTCGGCCCTGCGTCTGCTGATCGAGATTCTGGCGGAGCTGGCAGCCGGTAACGCGGTTCAGGTCGTACCGGTG
CATGCCGAATTGACGACCCAGGAAGCCGCCGACCTGCTCAACGTCTCACGTCCACACCTCATAAAACTGCTGGAAAGCGG
CGAGTTGTCCTACCACAAAACAGGCAAGCACCGACGTGTGCGTTTTGCCGATCTGATGGACTATAAGACCCGGCGCACCA
GCGCCAGCGAGCAGGCAATGGCGCTTCTCGCAGAGCAAGCTCAGGCGTTAAGGACAGGATACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References