Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 702761..703357 Replicon chromosome
Accession NZ_CP027561
Organism Pseudomonas fluorescens strain G7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6Y56_RS03020 Protein ID WP_085611238.1
Coordinates 703055..703357 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6Y56_RS03015 Protein ID WP_085609233.1
Coordinates 702761..703051 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6Y56_RS02995 699061..701181 - 2121 WP_169428668.1 TonB-dependent copper receptor -
C6Y56_RS03000 701266..701712 - 447 WP_169428669.1 DUF2946 domain-containing protein -
C6Y56_RS03005 701734..702213 - 480 WP_169428670.1 copper chaperone PCu(A)C -
C6Y56_RS03010 702262..702663 - 402 WP_169428671.1 DUF2946 domain-containing protein -
C6Y56_RS03015 702761..703051 - 291 WP_085609233.1 putative addiction module antidote protein Antitoxin
C6Y56_RS03020 703055..703357 - 303 WP_085611238.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6Y56_RS03025 703549..704277 - 729 WP_169428672.1 cobalt-precorrin-6A reductase -
C6Y56_RS03030 704274..705371 - 1098 WP_169428673.1 cobalt-precorrin-5B (C(1))-methyltransferase -
C6Y56_RS03035 705364..706575 - 1212 WP_169428674.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
C6Y56_RS03040 706720..708018 + 1299 WP_169428675.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11408.07 Da        Isoelectric Point: 9.4236

>T99463 WP_085611238.1 NZ_CP027561:c703357-703055 [Pseudomonas fluorescens]
MIEFERSPAFADWLDSMKDTNGKARIIARIRGAEHGNMGDCEFVGSAVYEMRVHYGPGYRMYFTRKGNVIYLLLLGGDKS
TQKRDIKRAIRMAQSIGNEE

Download         Length: 303 bp

>T99463 NZ_CP027561:c703357-703055 [Pseudomonas fluorescens]
ATGATCGAATTTGAACGATCCCCTGCATTTGCCGATTGGCTCGACTCGATGAAAGACACCAACGGCAAAGCTCGCATCAT
CGCCAGAATTCGAGGTGCAGAGCATGGAAATATGGGTGATTGCGAGTTCGTTGGCAGTGCCGTTTATGAAATGCGCGTTC
ATTACGGTCCCGGCTACAGGATGTACTTCACACGTAAAGGTAACGTGATTTATCTGCTACTGCTGGGGGGCGACAAGTCG
ACACAAAAACGAGATATCAAACGCGCCATCCGGATGGCGCAAAGCATCGGTAATGAGGAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10342.84 Da        Isoelectric Point: 4.7961

>AT99463 WP_085609233.1 NZ_CP027561:c703051-702761 [Pseudomonas fluorescens]
MTEKFTRFDAAEFLKTPEEMAAYLDACFDEDAGDGVLIRAALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATI
MKVMKALGLRLHAVAG

Download         Length: 291 bp

>AT99463 NZ_CP027561:c703051-702761 [Pseudomonas fluorescens]
ATGACCGAAAAATTCACCCGCTTCGACGCTGCAGAGTTTCTTAAAACGCCGGAGGAAATGGCGGCTTACCTGGACGCCTG
TTTTGACGAAGATGCTGGCGATGGCGTTCTCATCCGTGCAGCGCTTAATGACATTGCCCGCGCCCAAGGCATGACTCAGG
TTGCGCGGGATGCAGGTCTGGGTCGTGAAAGCCTTTATAAAGCGCTGAGCAGCACTGGAAATCCGGAATTCGCGACTATC
ATGAAAGTCATGAAGGCGCTGGGTTTGCGGTTGCATGCCGTAGCAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References