Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 3036957..3037909 Replicon chromosome
Accession NZ_CP027557
Organism Rhodococcus rhodochrous strain BX2

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag C6Y44_RS14115 Protein ID WP_159418169.1
Coordinates 3036957..3037526 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag C6Y44_RS14120 Protein ID WP_120282896.1
Coordinates 3037523..3037909 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6Y44_RS14095 3032138..3033253 + 1116 WP_159418172.1 FAD-dependent monooxygenase -
C6Y44_RS14100 3033297..3034244 + 948 WP_159418171.1 alpha/beta hydrolase -
C6Y44_RS14105 3034237..3035175 + 939 WP_120282890.1 MBL fold metallo-hydrolase -
C6Y44_RS14110 3035201..3036925 + 1725 WP_159418170.1 CocE/NonD family hydrolase -
C6Y44_RS14115 3036957..3037526 - 570 WP_159418169.1 zeta toxin family protein Toxin
C6Y44_RS14120 3037523..3037909 - 387 WP_120282896.1 hypothetical protein Antitoxin
C6Y44_RS14125 3038118..3039188 + 1071 WP_159418168.1 class I SAM-dependent methyltransferase -
C6Y44_RS14130 3039258..3039623 + 366 WP_120282900.1 HNH endonuclease -
C6Y44_RS14135 3041002..3041934 - 933 WP_159418167.1 TAXI family TRAP transporter solute-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-67)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20510.63 Da        Isoelectric Point: 10.6895

>T99461 WP_159418169.1 NZ_CP027557:c3037526-3036957 [Rhodococcus rhodochrous]
MRRLDLIVGPNGSGKSTFVELSLAPLLPRSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEAGFTVVLHVMLVPETMSVLRVQHRVASGGHAVPEDKIRARYRRLWPLVAEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPGALTGLG

Download         Length: 570 bp

>T99461 NZ_CP027557:c3037526-3036957 [Rhodococcus rhodochrous]
ATGAGGCGTCTGGATCTGATCGTCGGTCCCAACGGGTCCGGCAAGTCGACGTTCGTCGAGTTGTCCCTCGCTCCCCTGCT
GCCGCGCAGTGTGTTCGTCAACGCGGATGTGATCGCGCGGCAGCGGTGGCCCGATCGTGCCGAGGAGATGTCCTATGAGG
CGGCGCAACTCGCCGCGGCGGCGCGGGATCGGTTGCTGCGGCAGGGCCGGTCGTTCATCGCGGAGACGGTGTTCTCGCAT
CCGTCGAAGCTGGAGCTGATCGACCGCGCGCACGAGGCGGGGTTCACGGTGGTGCTGCACGTGATGCTGGTGCCCGAGAC
GATGTCGGTGCTGCGTGTGCAGCACCGGGTGGCCTCCGGTGGGCATGCGGTGCCCGAGGACAAGATCCGGGCGCGCTATC
GACGGTTGTGGCCGCTGGTGGCCGAGGCGATCGGCCGCGCCGATCAGGCGTCGGTGTACGACACGGCGTCCGGGACCCCG
GTGGTGGTGGCGCGGTTCGCGGGTGGGGTGCCGGTGGGTGCGGTGCGCTGGCCGGGGTGGGCGCCGGGGGCGCTCACCGG
GCTCGGCTGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14080.57 Da        Isoelectric Point: 4.7096

>AT99461 WP_120282896.1 NZ_CP027557:c3037909-3037523 [Rhodococcus rhodochrous]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYVEILAARGVTTVVLDDEGRLVEQRPDGSRRVLDDA

Download         Length: 387 bp

>AT99461 NZ_CP027557:c3037909-3037523 [Rhodococcus rhodochrous]
ATGACGTCGTCCACAGACAAGGTCACCCGCTTCGACGCCGAACTCGTCGACAGCGCCATCGCCGAGGGCGGCCGCCAGAA
TCGCACCGGACGCCAGCAACTCGAATACTGGGCCCGCATCGGCCGCGCGATGACCGCCCACGAGACCGCCTCCCTGCACC
GGGTGCACGAGGCGCTGGCCGGGACGCGGGAGCTGAGCGAACTCACCGCCGCCGAGGGCCGCTTGTTCGACGCGGAGATC
GATGCGCGCCTGGCGGACGGGCTGGCCCGCACCGACTACGTCGAGATCCTCGCCGCGCGTGGGGTCACCACGGTGGTGCT
CGACGACGAGGGCCGGTTGGTCGAGCAGCGTCCCGACGGTAGTCGCCGGGTGCTCGACGACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References