Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 954946..955180 | Replicon | chromosome |
| Accession | NZ_CP027555 | ||
| Organism | Escherichia coli strain 2013C-3513 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 954947..955050 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 954946..955180 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6991_RS06080 | 952144..952953 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| C6991_RS06085 | 953010..953204 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C6991_RS06090 | 953197..953385 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 953203..953381 | - | 179 | NuclAT_1 | - | - |
| - | 953203..953381 | - | 179 | NuclAT_1 | - | - |
| - | 953203..953381 | - | 179 | NuclAT_1 | - | - |
| - | 953203..953381 | - | 179 | NuclAT_1 | - | - |
| C6991_RS06095 | 953492..953773 | + | 282 | WP_001443927.1 | excisionase | - |
| C6991_RS06100 | 953739..954815 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 954946..955180 | + | 235 | - | - | Antitoxin |
| - | 954947..955050 | - | 104 | - | - | Toxin |
| C6991_RS06105 | 955208..955549 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C6991_RS06110 | 955562..956433 | - | 872 | Protein_1020 | copper homeostasis membrane protein CopD | - |
| C6991_RS06115 | 956437..956811 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C6991_RS06120 | 956950..957180 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C6991_RS06125 | 957282..957938 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C6991_RS06130 | 957962..958624 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 907376..958624 | 51248 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T99438 NZ_CP027555:c955050-954947 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT99438 NZ_CP027555:954946-955180 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
