Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3762390..3762624 | Replicon | chromosome |
| Accession | NZ_CP027552 | ||
| Organism | Escherichia coli strain 2015C-4498 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3762391..3762494 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3762390..3762624 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6953_RS20200 | 3759338..3760390 | + | 1053 | Protein_3667 | recombinase RecT | - |
| C6953_RS20205 | 3760454..3760648 | + | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C6953_RS20210 | 3760641..3760829 | + | 189 | WP_024177035.1 | DUF1187 family protein | - |
| - | 3760647..3760825 | - | 179 | NuclAT_0 | - | - |
| - | 3760647..3760825 | - | 179 | NuclAT_0 | - | - |
| - | 3760647..3760825 | - | 179 | NuclAT_0 | - | - |
| - | 3760647..3760825 | - | 179 | NuclAT_0 | - | - |
| C6953_RS20215 | 3760936..3761217 | + | 282 | WP_005127484.1 | excisionase | - |
| C6953_RS20220 | 3761183..3762259 | + | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3762390..3762624 | + | 235 | - | - | Antitoxin |
| - | 3762391..3762494 | - | 104 | - | - | Toxin |
| C6953_RS20225 | 3762652..3762993 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C6953_RS20230 | 3763006..3763878 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| C6953_RS20235 | 3763882..3764256 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C6953_RS20240 | 3764395..3764625 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C6953_RS20245 | 3764727..3765383 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C6953_RS20250 | 3765407..3766069 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3714049..3770034 | 55985 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T99405 NZ_CP027552:c3762494-3762391 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT99405 NZ_CP027552:3762390-3762624 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
