Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1572015..1572249 | Replicon | chromosome |
| Accession | NZ_CP027546 | ||
| Organism | Escherichia coli strain 2013C-4187 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1572016..1572119 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1572015..1572249 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6993_RS09120 | 1569213..1570022 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| C6993_RS09125 | 1570079..1570273 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C6993_RS09130 | 1570266..1570454 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1570272..1570450 | - | 179 | NuclAT_1 | - | - |
| - | 1570272..1570450 | - | 179 | NuclAT_1 | - | - |
| - | 1570272..1570450 | - | 179 | NuclAT_1 | - | - |
| - | 1570272..1570450 | - | 179 | NuclAT_1 | - | - |
| C6993_RS09135 | 1570561..1570842 | + | 282 | WP_001443927.1 | excisionase | - |
| C6993_RS09140 | 1570808..1571884 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1572015..1572249 | + | 235 | - | - | Antitoxin |
| - | 1572016..1572119 | - | 104 | - | - | Toxin |
| C6993_RS09145 | 1572277..1572618 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C6993_RS09150 | 1572631..1573503 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| C6993_RS09155 | 1573507..1573881 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C6993_RS09160 | 1574020..1574250 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C6993_RS09165 | 1574352..1575008 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C6993_RS09170 | 1575032..1575694 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 1522358..1579032 | 56674 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T99307 NZ_CP027546:c1572119-1572016 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT99307 NZ_CP027546:1572015-1572249 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
