Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1640410..1640550 Replicon chromosome
Accession NZ_CP027533
Organism Serratia marcescens strain AR_0091

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1640454..1640550 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1640410..1640550 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM470_RS08060 1635612..1636037 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
AM470_RS08065 1636230..1637183 + 954 WP_033646426.1 prolyl aminopeptidase -
AM470_RS08070 1637215..1637445 - 231 WP_033642715.1 DNA polymerase III subunit theta -
AM470_RS08075 1637791..1638309 + 519 WP_025302449.1 non-heme ferritin -
AM470_RS08080 1638634..1639017 + 384 WP_004940886.1 CopC domain-containing protein YobA -
AM470_RS08085 1639020..1639901 + 882 WP_060428500.1 copper homeostasis membrane protein CopD -
AM470_RS08090 1639971..1640312 + 342 WP_025302452.1 YebY family protein -
- 1640410..1640550 - 141 - - Antitoxin
- 1640454..1640550 + 97 - - Toxin
AM470_RS08095 1640803..1641207 + 405 WP_033646424.1 hypothetical protein -
AM470_RS08100 1641204..1641422 - 219 WP_033638114.1 hypothetical protein -
AM470_RS25485 1641496..1641645 - 150 WP_154619228.1 hypothetical protein -
AM470_RS08105 1641937..1642287 + 351 WP_060428502.1 DUF4377 domain-containing protein -
AM470_RS08110 1642471..1643670 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
AM470_RS08115 1643898..1644116 + 219 WP_033646423.1 hypothetical protein -
AM470_RS08120 1644288..1644593 + 306 WP_033646422.1 hypothetical protein -
AM470_RS08125 1644637..1644972 + 336 WP_033638120.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T99173 NZ_CP027533:1640454-1640550 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT99173 NZ_CP027533:c1640550-1640410 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References