Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1673933..1674590 Replicon chromosome
Accession NZ_CP027482
Organism Aeromicrobium sp. A1-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C6I20_RS08085 Protein ID WP_118395489.1
Coordinates 1673933..1674361 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C6I20_RS08090 Protein ID WP_118395490.1
Coordinates 1674351..1674590 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6I20_RS08060 1669126..1670379 + 1254 WP_162891219.1 oxidoreductase -
C6I20_RS08065 1670376..1670576 + 201 WP_118395485.1 ferredoxin -
C6I20_RS08070 1670579..1672072 - 1494 WP_162891220.1 serine/threonine protein kinase -
C6I20_RS08075 1672143..1673123 - 981 WP_162891221.1 DUF3662 domain-containing protein -
C6I20_RS08080 1673194..1673922 + 729 WP_162891222.1 hypothetical protein -
C6I20_RS08085 1673933..1674361 - 429 WP_118395489.1 PIN domain-containing protein Toxin
C6I20_RS08090 1674351..1674590 - 240 WP_118395490.1 CopG family transcriptional regulator Antitoxin
C6I20_RS08095 1674649..1675305 - 657 WP_162891223.1 hypothetical protein -
C6I20_RS08100 1675470..1676036 + 567 WP_118395492.1 hypothetical protein -
C6I20_RS08105 1676040..1676972 - 933 WP_118395493.1 NADP-dependent oxidoreductase -
C6I20_RS08110 1676969..1677334 - 366 WP_118395494.1 hypothetical protein -
C6I20_RS08115 1677439..1677918 + 480 WP_118395495.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1641476..1676036 34560


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-140)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15767.01 Da        Isoelectric Point: 6.2084

>T99130 WP_118395489.1 NZ_CP027482:c1674361-1673933 [Aeromicrobium sp. A1-2]
MIVDANILIYAANTSASAHEPARQWLEDQLNGEVRVGLPWPSLLAFMRLTTSPRMSRFPISGQQAWAIVQSWLASPVAWI
PATTPHHVEIFSALVDKYQIHSNLVPDAHLAAYAIEHSVPLASADTDFARFSELRWVNPVAI

Download         Length: 429 bp

>T99130 NZ_CP027482:c1674361-1673933 [Aeromicrobium sp. A1-2]
ATGATCGTTGACGCGAACATCTTGATCTACGCAGCCAACACCTCGGCGAGCGCACATGAGCCAGCCAGGCAATGGTTGGA
GGATCAGCTCAACGGTGAAGTCCGGGTTGGTCTGCCGTGGCCTTCGCTATTGGCTTTCATGAGACTCACGACGAGCCCAC
GCATGTCCCGCTTCCCCATCTCTGGCCAGCAGGCCTGGGCAATCGTGCAGTCGTGGCTCGCGTCGCCGGTCGCGTGGATA
CCTGCCACGACACCGCACCACGTCGAGATCTTCTCCGCGCTGGTCGACAAGTACCAGATCCACAGCAATCTCGTTCCGGA
TGCACACCTGGCCGCGTATGCGATCGAGCACAGTGTTCCGCTGGCCTCGGCCGACACAGACTTTGCTCGTTTCAGCGAAT
TGCGCTGGGTCAACCCGGTCGCGATCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8502.45 Da        Isoelectric Point: 3.9696

>AT99130 WP_118395490.1 NZ_CP027482:c1674590-1674351 [Aeromicrobium sp. A1-2]
MRSTVNFDDDVIAVVERLRALEQLGFSEAVNRLARAGASVVGADVERPAFVQPTVDLGQMTDVSNVAEALELAEANDDR

Download         Length: 240 bp

>AT99130 NZ_CP027482:c1674590-1674351 [Aeromicrobium sp. A1-2]
ATGAGGAGCACGGTGAATTTCGATGACGATGTCATCGCGGTGGTGGAAAGGCTGAGAGCCCTGGAGCAACTGGGCTTCAG
CGAGGCAGTGAATCGGCTCGCTCGGGCCGGTGCCTCGGTGGTGGGTGCCGACGTCGAACGGCCTGCCTTCGTGCAGCCGA
CGGTAGATCTGGGCCAGATGACAGACGTGTCCAATGTGGCCGAAGCGCTGGAGCTGGCGGAGGCGAACGATGATCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References