Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 976970..977204 Replicon chromosome
Accession NZ_CP027472
Organism Escherichia coli strain 2014C-3050

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 977100..977203 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 976970..977204 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAF93_RS05020 973525..974187 - 663 WP_000944256.1 exodeoxyribonuclease X -
AAF93_RS05025 974211..974867 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AAF93_RS05030 974969..975199 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AAF93_RS05035 975338..975712 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AAF93_RS05040 975716..976588 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AAF93_RS05045 976601..976942 + 342 WP_000976492.1 YebY family protein -
- 976970..977204 - 235 - - Antitoxin
- 977100..977203 + 104 - - Toxin
AAF93_RS05050 977335..978411 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
AAF93_RS05055 978377..978658 - 282 WP_001443927.1 excisionase -
AAF93_RS05060 978765..978953 - 189 WP_001356607.1 DUF1187 family protein -
- 978769..978947 + 179 NuclAT_1 - -
- 978769..978947 + 179 NuclAT_1 - -
- 978769..978947 + 179 NuclAT_1 - -
- 978769..978947 + 179 NuclAT_1 - -
AAF93_RS05065 978946..979140 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
AAF93_RS05070 979197..980007 - 811 Protein_937 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 971468..1026898 55430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99098 NZ_CP027472:977100-977203 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT99098 NZ_CP027472:c977204-976970 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References