Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1862443..1862714 Replicon chromosome
Accession NZ_CP027462
Organism Escherichia coli isolate 07-4299

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1862573..1862676 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1862443..1862714 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W75_RS09585 1858998..1859660 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6W75_RS09590 1859684..1860340 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6W75_RS09595 1860442..1860672 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6W75_RS09600 1860811..1861185 + 375 WP_000204700.1 CopC domain-containing protein YobA -
C6W75_RS09605 1861189..1862061 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6W75_RS09610 1862074..1862415 + 342 WP_000976472.1 YebY family protein -
- 1862443..1862714 - 272 - - Antitoxin
- 1862573..1862676 + 104 - - Toxin
C6W75_RS09615 1862811..1863467 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
C6W75_RS09620 1863468..1863659 - 192 WP_001296140.1 YebW family protein -
C6W75_RS09625 1863764..1864000 - 237 WP_001295499.1 DUF1480 family protein -
C6W75_RS09630 1864118..1865557 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99078 NZ_CP027462:1862573-1862676 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT99078 NZ_CP027462:c1862714-1862443 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References