Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4724709..4724980 Replicon chromosome
Accession NZ_CP027457
Organism Escherichia coli strain 88-3493

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4724747..4724850 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4724709..4724980 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W79_RS23980 4721866..4723305 + 1440 WP_024192321.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C6W79_RS23985 4723423..4723659 + 237 WP_001295499.1 DUF1480 family protein -
C6W79_RS23990 4723764..4723955 + 192 WP_001338167.1 YebW family protein -
C6W79_RS23995 4723956..4724612 - 657 WP_000812739.1 protein-serine/threonine phosphatase -
- 4724709..4724980 + 272 - - Antitoxin
- 4724747..4724850 - 104 - - Toxin
C6W79_RS24000 4725008..4725349 - 342 WP_000976472.1 YebY family protein -
C6W79_RS24005 4725362..4726234 - 873 WP_032300815.1 copper homeostasis membrane protein CopD -
C6W79_RS24010 4726238..4726612 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C6W79_RS24015 4726751..4726981 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C6W79_RS24020 4727083..4727739 + 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
C6W79_RS24025 4727763..4728425 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99008 NZ_CP027457:c4724850-4724747 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT99008 NZ_CP027457:4724709-4724980 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References