Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4218028..4218299 Replicon chromosome
Accession NZ_CP027449
Organism Escherichia coli strain 2014C-3097

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4218158..4218261 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4218028..4218299 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W73_RS21615 4214583..4215245 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6W73_RS21620 4215269..4215925 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6W73_RS21625 4216027..4216257 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6W73_RS21630 4216396..4216770 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C6W73_RS21635 4216774..4217646 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6W73_RS21640 4217659..4218000 + 342 WP_000976492.1 YebY family protein -
- 4218028..4218299 - 272 - - Antitoxin
- 4218158..4218261 + 104 - - Toxin
C6W73_RS21645 4218396..4219052 + 657 WP_000812723.1 protein-serine/threonine phosphatase -
C6W73_RS21650 4219053..4219244 - 192 WP_001338167.1 YebW family protein -
C6W73_RS21655 4219349..4219585 - 237 WP_001295499.1 DUF1480 family protein -
C6W73_RS21660 4219703..4221142 - 1440 WP_106879209.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98912 NZ_CP027449:4218158-4218261 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98912 NZ_CP027449:c4218299-4218028 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References