Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5162225..5162496 Replicon chromosome
Accession NZ_CP027445
Organism Escherichia coli strain 2013C-3492

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5162355..5162458 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5162225..5162496 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W68_RS27535 5158781..5159443 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6W68_RS27540 5159467..5160123 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
C6W68_RS27545 5160225..5160455 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6W68_RS27550 5160594..5160968 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C6W68_RS27555 5160972..5161843 + 872 Protein_5030 copper homeostasis membrane protein CopD -
C6W68_RS27560 5161856..5162197 + 342 WP_000976472.1 YebY family protein -
- 5162225..5162496 - 272 - - Antitoxin
- 5162355..5162458 + 104 - - Toxin
C6W68_RS27565 5162593..5163249 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C6W68_RS27570 5163250..5163441 - 192 WP_001296140.1 YebW family protein -
C6W68_RS27575 5163546..5163782 - 237 WP_001295499.1 DUF1480 family protein -
C6W68_RS27580 5163900..5165337 - 1438 Protein_5035 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98853 NZ_CP027445:5162355-5162458 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCACCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98853 NZ_CP027445:c5162496-5162225 [Escherichia coli]
AAAGTCAGCGAAGGGAATGTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGTGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCC
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References