Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1064926..1065160 Replicon chromosome
Accession NZ_CP027442
Organism Escherichia coli strain 2013C-3252

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1064927..1065030 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1064926..1065160 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJ69_RS06500 1062124..1062933 + 810 WP_000166317.1 recombination protein RecT -
MJ69_RS06505 1062990..1063184 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
MJ69_RS06510 1063177..1063365 + 189 WP_001356607.1 DUF1187 family protein -
- 1063183..1063361 - 179 NuclAT_1 - -
- 1063183..1063361 - 179 NuclAT_1 - -
- 1063183..1063361 - 179 NuclAT_1 - -
- 1063183..1063361 - 179 NuclAT_1 - -
MJ69_RS06515 1063472..1063753 + 282 WP_001443927.1 excisionase -
MJ69_RS06520 1063719..1064795 + 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
- 1064926..1065160 + 235 - - Antitoxin
- 1064927..1065030 - 104 - - Toxin
MJ69_RS06525 1065188..1065529 - 342 WP_000976492.1 YebY family protein -
MJ69_RS06530 1065542..1066414 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
MJ69_RS06535 1066418..1066792 - 375 WP_000204699.1 CopC domain-containing protein YobA -
MJ69_RS06540 1066931..1067161 + 231 WP_000916763.1 DNA polymerase III subunit theta -
MJ69_RS06545 1067263..1067919 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
MJ69_RS06550 1067943..1068605 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 971092..1072570 101478


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98812 NZ_CP027442:c1065030-1064927 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT98812 NZ_CP027442:1064926-1065160 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References