Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 1064926..1065160 | Replicon | chromosome |
Accession | NZ_CP027442 | ||
Organism | Escherichia coli strain 2013C-3252 |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 1064927..1065030 (-) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 1064926..1065160 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MJ69_RS06500 | 1062124..1062933 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
MJ69_RS06505 | 1062990..1063184 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
MJ69_RS06510 | 1063177..1063365 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
- | 1063183..1063361 | - | 179 | NuclAT_1 | - | - |
- | 1063183..1063361 | - | 179 | NuclAT_1 | - | - |
- | 1063183..1063361 | - | 179 | NuclAT_1 | - | - |
- | 1063183..1063361 | - | 179 | NuclAT_1 | - | - |
MJ69_RS06515 | 1063472..1063753 | + | 282 | WP_001443927.1 | excisionase | - |
MJ69_RS06520 | 1063719..1064795 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
- | 1064926..1065160 | + | 235 | - | - | Antitoxin |
- | 1064927..1065030 | - | 104 | - | - | Toxin |
MJ69_RS06525 | 1065188..1065529 | - | 342 | WP_000976492.1 | YebY family protein | - |
MJ69_RS06530 | 1065542..1066414 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
MJ69_RS06535 | 1066418..1066792 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
MJ69_RS06540 | 1066931..1067161 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
MJ69_RS06545 | 1067263..1067919 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
MJ69_RS06550 | 1067943..1068605 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | nleG7' | 971092..1072570 | 101478 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98812 NZ_CP027442:c1065030-1064927 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98812 NZ_CP027442:1064926-1065160 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT