Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 204717..204985 Replicon chromosome
Accession NZ_CP027437
Organism Escherichia coli strain 2012C-4221

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 204844..204947 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 204717..204985 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W65_RS01185 201270..201932 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6W65_RS01190 201956..202612 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
C6W65_RS01195 202714..202944 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6W65_RS01200 203083..203457 + 375 WP_106905904.1 CopC domain-containing protein YobA -
C6W65_RS01205 203461..204333 + 873 WP_106905905.1 copper homeostasis membrane protein CopD -
C6W65_RS01210 204346..204687 + 342 WP_000976472.1 YebY family protein -
- 204717..204985 - 269 - - Antitoxin
- 204844..204947 + 104 - - Toxin
C6W65_RS01215 205082..205738 + 657 WP_025210567.1 protein-serine/threonine phosphatase -
C6W65_RS01220 205739..205930 - 192 WP_001296140.1 YebW family protein -
C6W65_RS01225 206035..206271 - 237 WP_096987357.1 DUF1480 family protein -
C6W65_RS01230 206389..207828 - 1440 WP_106906903.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 197405..220825 23420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98745 NZ_CP027437:204844-204947 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT98745 NZ_CP027437:c204985-204717 [Escherichia coli]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References