Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1430003..1430502 Replicon chromosome
Accession NZ_CP027433
Organism Gordonia iterans strain Co17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C6V83_RS06715 Protein ID WP_159067459.1
Coordinates 1430003..1430242 (-) Length 80 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C6V83_RS06720 Protein ID WP_105941739.1
Coordinates 1430278..1430502 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6V83_RS06690 1426052..1426294 + 243 WP_105941733.1 hypothetical protein -
C6V83_RS06695 1426291..1426671 + 381 WP_105941734.1 type II toxin-antitoxin system VapC family toxin -
C6V83_RS06700 1426723..1428219 + 1497 WP_105941735.1 MucR family transcriptional regulator -
C6V83_RS06705 1428236..1429444 + 1209 WP_105941736.1 hypothetical protein -
C6V83_RS06710 1429441..1429902 + 462 WP_105941737.1 NADAR family protein -
C6V83_RS06715 1430003..1430242 - 240 WP_159067459.1 hypothetical protein Toxin
C6V83_RS06720 1430278..1430502 - 225 WP_105941739.1 ribbon-helix-helix protein, CopG family Antitoxin
C6V83_RS06725 1430766..1432349 + 1584 WP_105941740.1 glutamine-hydrolyzing GMP synthase -
C6V83_RS06730 1432653..1432862 - 210 WP_105941741.1 hypothetical protein -
C6V83_RS06735 1432859..1434193 - 1335 WP_105941742.1 PspC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(9-34)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 8634.88 Da        Isoelectric Point: 4.7254

>T98710 WP_159067459.1 NZ_CP027433:c1430242-1430003 [Gordonia iterans]
MPPISEMPVAPTSAHVDRRALEVQDRLAQRGHHRAAIVPDLLIAAIAEYADLTVLHVDKDFELIAGVADQPIERLAGDF

Download         Length: 240 bp

>T98710 NZ_CP027433:c1430242-1430003 [Gordonia iterans]
ATGCCGCCCATCTCTGAAATGCCCGTCGCCCCGACATCCGCACACGTCGACCGCCGAGCGCTCGAAGTGCAGGACCGGCT
CGCGCAACGCGGGCATCATCGCGCAGCAATAGTCCCCGACCTCCTGATCGCCGCGATCGCCGAGTACGCGGACCTCACCG
TGCTGCACGTCGACAAGGATTTCGAACTGATCGCCGGCGTCGCCGACCAGCCGATCGAGCGACTCGCAGGAGACTTCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8462.55 Da        Isoelectric Point: 4.6038

>AT98710 WP_105941739.1 NZ_CP027433:c1430502-1430278 [Gordonia iterans]
VTDILIRNIDDDDLRHIDALAAELGISRSELLRRETKDLARRHALQQVTLDDIRRSVDLAQGVLDEDLMKQAWG

Download         Length: 225 bp

>AT98710 NZ_CP027433:c1430502-1430278 [Gordonia iterans]
GTGACTGACATCCTGATCCGCAACATCGACGACGACGATCTCAGACACATCGACGCCCTGGCGGCAGAGCTGGGAATCTC
CCGGAGTGAACTCTTGCGCAGGGAAACCAAAGACCTGGCGCGGCGGCATGCGCTGCAGCAGGTCACCCTCGACGACATCC
GCCGCTCTGTGGACCTGGCGCAGGGCGTCCTCGACGAGGATCTGATGAAGCAGGCCTGGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References