Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 944855..945510 Replicon chromosome
Accession NZ_CP027433
Organism Gordonia iterans strain Co17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C6V83_RS04365 Protein ID WP_105941365.1
Coordinates 944855..945265 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C6V83_RS04370 Protein ID WP_105941366.1
Coordinates 945262..945510 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6V83_RS04340 940222..942060 + 1839 WP_105941361.1 adenylyl-sulfate kinase -
C6V83_RS04345 942123..943388 + 1266 WP_105943711.1 serine/threonine protein kinase -
C6V83_RS04350 943427..943888 - 462 WP_105941362.1 hypothetical protein -
C6V83_RS04355 943888..944319 - 432 WP_105941363.1 hypothetical protein -
C6V83_RS04360 944389..944811 - 423 WP_105941364.1 hypothetical protein -
C6V83_RS04365 944855..945265 - 411 WP_105941365.1 type II toxin-antitoxin system VapC family toxin Toxin
C6V83_RS04370 945262..945510 - 249 WP_105941366.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
C6V83_RS04375 945537..947360 - 1824 WP_105941367.1 type VII secretion AAA-ATPase EccA -
C6V83_RS04380 947474..949759 + 2286 WP_199832584.1 phosphoribosylformylglycinamidine synthase subunit PurL -
C6V83_RS04385 949782..950237 + 456 WP_105941369.1 DUF2752 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-122)

Antitoxin

Antitoxin VapB-like

(1-80)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14620.40 Da        Isoelectric Point: 4.4937

>T98709 WP_105941365.1 NZ_CP027433:c945265-944855 [Gordonia iterans]
MIVDTSAIIAVLAGESDARQLAEAIDRGQPKMSAATYLECSIVLDRKGPPEASRRFDAWFRSLGIEIVPVTVEQAIIARA
AYRDFGRGSGHRAGLNFGDCFSYALAAESGESLLWKGDDFGHTGIPSALDQPEGFE

Download         Length: 411 bp

>T98709 NZ_CP027433:c945265-944855 [Gordonia iterans]
ATGATCGTTGACACTTCGGCGATCATCGCCGTACTCGCGGGCGAGTCCGACGCCCGGCAACTCGCCGAGGCGATCGACCG
CGGTCAGCCCAAGATGTCGGCAGCGACCTATCTCGAATGCTCGATCGTCCTCGATCGGAAGGGGCCACCCGAGGCCAGCC
GCAGGTTCGACGCTTGGTTTAGATCGCTCGGGATCGAGATCGTGCCGGTAACCGTCGAGCAGGCGATCATTGCGCGGGCC
GCCTATCGGGACTTCGGCAGGGGCAGCGGGCATCGGGCCGGACTGAACTTCGGCGACTGCTTCTCGTACGCACTCGCAGC
AGAATCCGGCGAGTCGCTGCTCTGGAAGGGCGACGACTTCGGGCACACGGGCATCCCCTCAGCGCTCGATCAACCGGAAG
GTTTTGAGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.21 Da        Isoelectric Point: 6.7265

>AT98709 WP_105941366.1 NZ_CP027433:c945510-945262 [Gordonia iterans]
MAMHIRDRRAHELVKEIAALSGTSQEAAVRAAVEHYAAMLRRRQGSRVEAVLNEGADIGRSFGLRRGEDPTADLYDDDGL
LR

Download         Length: 249 bp

>AT98709 NZ_CP027433:c945510-945262 [Gordonia iterans]
ATGGCGATGCACATCCGCGATCGGCGCGCTCACGAGCTGGTGAAAGAAATCGCGGCTCTCTCCGGCACGTCCCAGGAGGC
GGCCGTCCGCGCAGCAGTCGAGCACTACGCGGCGATGCTGCGGCGTAGGCAAGGCAGCCGCGTGGAGGCGGTTCTCAACG
AAGGCGCCGACATCGGTCGATCGTTCGGTCTACGCCGGGGCGAGGACCCGACAGCAGACCTGTACGACGACGACGGACTG
CTGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References