Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 685867..686392 Replicon chromosome
Accession NZ_CP027417
Organism Oligella urethralis strain FDAARGOS_329

Toxin (Protein)


Gene name relE Uniprot ID A0A095YW52
Locus tag CEQ07_RS03185 Protein ID WP_018025640.1
Coordinates 685867..686151 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A096A6L2
Locus tag CEQ07_RS03190 Protein ID WP_018025641.1
Coordinates 686141..686392 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ07_RS03175 682109..685561 + 3453 WP_105885110.1 UvrD-helicase domain-containing protein -
CEQ07_RS03185 685867..686151 - 285 WP_018025640.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CEQ07_RS03190 686141..686392 - 252 WP_018025641.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CEQ07_RS03200 687381..688181 + 801 WP_105885111.1 cell filamentation protein Fic -
CEQ07_RS03205 688337..690352 + 2016 WP_105885112.1 DNA polymerase III subunit gamma/tau -
CEQ07_RS03210 690402..690728 + 327 WP_026156738.1 YbaB/EbfC family nucleoid-associated protein -
CEQ07_RS03215 690767..691381 + 615 WP_026156739.1 recombination mediator RecR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 676646..690352 13706


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-70)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11223.31 Da        Isoelectric Point: 10.6683

>T98662 WP_018025640.1 NZ_CP027417:c686151-685867 [Oligella urethralis]
MTYRLFFKAEAEKEWRKLDLTIKRQFKKKLTECLKNPHIPSARLTGMKNCYKIKLQSTGYRLVYEVRDKELVVSVVAIGK
RERNEVYNTAIKRI

Download         Length: 285 bp

>T98662 NZ_CP027417:c686151-685867 [Oligella urethralis]
ATGACTTATAGGTTATTTTTTAAAGCCGAAGCTGAAAAAGAATGGAGAAAGCTTGATCTTACAATAAAGCGACAATTTAA
AAAGAAACTAACTGAGTGTTTGAAAAACCCTCACATACCGTCAGCAAGATTAACTGGAATGAAAAATTGCTATAAAATTA
AATTGCAAAGCACTGGATACAGGCTAGTCTATGAGGTTAGAGATAAGGAGTTAGTGGTTTCGGTAGTAGCTATTGGTAAA
CGAGAACGCAACGAAGTTTATAACACAGCAATTAAACGTATTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9418.77 Da        Isoelectric Point: 4.2412

>AT98662 WP_018025641.1 NZ_CP027417:c686392-686141 [Oligella urethralis]
MSIRQIYANNSTSISELKKNPMAVMKQAEGFPVVVLNRNQPVFYCVPADAYEALMDKLEDMELADIVRQRQNSPEVEVSL
DDL

Download         Length: 252 bp

>AT98662 NZ_CP027417:c686392-686141 [Oligella urethralis]
ATGTCAATCCGTCAAATTTATGCTAACAATTCAACTAGTATTAGTGAATTAAAAAAGAATCCGATGGCTGTAATGAAACA
AGCAGAAGGATTTCCAGTCGTTGTATTAAATCGTAATCAGCCTGTTTTTTACTGTGTTCCTGCGGATGCCTATGAGGCTT
TAATGGATAAACTTGAGGATATGGAGCTAGCTGACATTGTGAGACAACGACAAAACTCACCAGAAGTAGAGGTTTCGCTT
GATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A095YW52

Antitoxin

Source ID Structure
AlphaFold DB A0A096A6L2

References