Detailed information of TA system TA098642

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2695261..2695727
• Replicon: chromosome
• Accession: NZ_CP027397
• Organism: Yersinia intermedia strain FDAARGOS_358

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CEQ36_RS12765
• Protein ID: WP_050088509.1
• Coordinates: 2695452..2695727 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CEQ36_RS12760
• Protein ID: WP_050288746.1
• Coordinates: 2695261..2695452 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEQ36_RS12745	2690491..2691648	+	1158	WP_005188243.1	alcohol dehydrogenase	-
CEQ36_RS12750	2691965..2692798	+	834	WP_080607975.1	2,5-didehydrogluconate reductase DkgA	-
CEQ36_RS12755	2692820..2695090	-	2271	WP_005188248.1	YgiQ family radical SAM protein	-
CEQ36_RS12760	2695261..2695452	+	192	WP_050288746.1	hypothetical protein	Antitoxin
CEQ36_RS12765	2695452..2695727	+	276	WP_050088509.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
CEQ36_RS12770	2695874..2697301	-	1428	WP_005188253.1	cell division protein FtsP	-
CEQ36_RS12775	2697473..2698213	-	741	WP_050073901.1	1-acylglycerol-3-phosphate O-acyltransferase	-
CEQ36_RS12780	2698436..2700703	-	2268	WP_042569053.1	DNA topoisomerase IV subunit A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10460.94 Da
• Isoelectric Point: 4.7385

>T98642 WP_050088509.1 NZ_CP027397:2695452-2695727 [Yersinia intermedia]
MLPIKWTDEAKTDLYALIAFITEENPYAAESLLHQLEDSVLPATEHPYMFRSGRVPGTREMVAHPNYVIIYQVMADQISV
LNVVHSRQEYP

Nucleotide

• Length: 276 bp

>T98642 NZ_CP027397:2695452-2695727 [Yersinia intermedia]
ATGCTCCCTATAAAATGGACTGACGAAGCAAAGACGGATCTTTATGCACTAATCGCGTTCATCACAGAAGAAAACCCTTA
CGCAGCAGAATCACTACTTCACCAACTGGAAGACTCCGTTCTTCCTGCTACTGAGCATCCCTATATGTTTCGCTCAGGTA
GAGTTCCTGGCACTCGAGAAATGGTGGCGCATCCCAATTACGTTATTATTTATCAGGTGATGGCTGACCAAATCAGCGTG
TTAAACGTTGTTCACTCTCGACAGGAATACCCGTAG

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7176.21 Da
• Isoelectric Point: 7.0117

>AT98642 WP_050288746.1 NZ_CP027397:2695261-2695452 [Yersinia intermedia]
MSTKLSPIVSEFETEEQAESYDLWFRAKVEASMNSPKPQIPHDEVMAGARKIIEQAKARRKLA

Nucleotide

• Length: 192 bp

>AT98642 NZ_CP027397:2695261-2695452 [Yersinia intermedia]
ATGAGCACTAAATTATCACCAATCGTCTCTGAATTTGAAACCGAAGAACAGGCGGAAAGCTACGATCTTTGGTTCCGGGC
TAAGGTCGAGGCATCAATGAATAGCCCCAAACCCCAAATTCCTCACGATGAAGTCATGGCGGGTGCGCGCAAAATTATTG
AACAAGCCAAAGCACGGAGGAAGCTGGCTTAA