Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 811444..811715 Replicon chromosome
Accession NZ_CP027394
Organism Escherichia coli O104:H4 strain FDAARGOS_349

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 811482..811585 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 811444..811715 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ27_RS05065 808601..810040 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CEQ27_RS05070 810158..810394 + 237 WP_001295499.1 DUF1480 family protein -
CEQ27_RS05075 810499..810690 + 192 WP_001296140.1 YebW family protein -
CEQ27_RS05080 810691..811347 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 811444..811715 + 272 - - Antitoxin
- 811482..811585 - 104 - - Toxin
CEQ27_RS05085 811743..812084 - 342 WP_000976472.1 YebY family protein -
CEQ27_RS05090 812097..812969 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CEQ27_RS05095 812973..813347 - 375 WP_000204699.1 CopC domain-containing protein YobA -
CEQ27_RS05100 813486..813716 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CEQ27_RS05105 813818..814474 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CEQ27_RS05110 814498..815160 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98602 NZ_CP027394:c811585-811482 [Escherichia coli O104:H4]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98602 NZ_CP027394:811444-811715 [Escherichia coli O104:H4]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References