Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 594926..595160 | Replicon | chromosome |
| Accession | NZ_CP027390 | ||
| Organism | Escherichia coli strain 2015C-4944 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 595056..595159 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 594926..595160 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AX062_RS03145 | 591481..592143 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| AX062_RS03150 | 592167..592823 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| AX062_RS03155 | 592925..593155 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AX062_RS03160 | 593294..593668 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| AX062_RS03165 | 593672..594544 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| AX062_RS03170 | 594557..594898 | + | 342 | WP_000976492.1 | YebY family protein | - |
| - | 594926..595160 | - | 235 | - | - | Antitoxin |
| - | 595056..595159 | + | 104 | - | - | Toxin |
| AX062_RS03175 | 595251..596366 | - | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| AX062_RS03180 | 596332..596613 | - | 282 | WP_001443927.1 | excisionase | - |
| AX062_RS03185 | 596720..596908 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 596724..596902 | + | 179 | NuclAT_1 | - | - |
| - | 596724..596902 | + | 179 | NuclAT_1 | - | - |
| - | 596724..596902 | + | 179 | NuclAT_1 | - | - |
| - | 596724..596902 | + | 179 | NuclAT_1 | - | - |
| AX062_RS03190 | 596901..597095 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| AX062_RS03195 | 597152..597559 | - | 408 | Protein_591 | recombinase RecT | - |
| AX062_RS03205 | 598824..599228 | - | 405 | Protein_593 | recombinase RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 589424..661668 | 72244 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98561 NZ_CP027390:595056-595159 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98561 NZ_CP027390:c595160-594926 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
