Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4278389..4278623 Replicon chromosome
Accession NZ_CP027387
Organism Escherichia coli strain 2014C-3057

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4278519..4278622 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4278389..4278623 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6P73_RS22650 4274944..4275606 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6P73_RS22655 4275630..4276286 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6P73_RS22660 4276388..4276618 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6P73_RS22665 4276757..4277131 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C6P73_RS22670 4277135..4278007 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6P73_RS22675 4278020..4278361 + 342 WP_000976492.1 YebY family protein -
- 4278389..4278623 - 235 - - Antitoxin
- 4278519..4278622 + 104 - - Toxin
C6P73_RS22680 4278714..4279829 - 1116 WP_001189092.1 phage integrase Arm DNA-binding domain-containing protein -
C6P73_RS22685 4279795..4280076 - 282 WP_001443927.1 excisionase -
C6P73_RS22690 4280183..4280371 - 189 WP_001356607.1 DUF1187 family protein -
- 4280187..4280365 + 179 NuclAT_1 - -
- 4280187..4280365 + 179 NuclAT_1 - -
- 4280187..4280365 + 179 NuclAT_1 - -
- 4280187..4280365 + 179 NuclAT_1 - -
C6P73_RS22695 4280364..4280558 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
C6P73_RS22700 4280615..4281424 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 4272887..4343866 70979


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98505 NZ_CP027387:4278519-4278622 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT98505 NZ_CP027387:c4278623-4278389 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References