Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995209..1995480 Replicon chromosome
Accession NZ_CP027380
Organism Escherichia coli strain 2013C-3250

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995339..1995442 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995209..1995480 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYN27_RS10920 1991764..1992426 - 663 WP_000944256.1 exodeoxyribonuclease X -
AYN27_RS10925 1992450..1993106 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AYN27_RS10930 1993208..1993438 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AYN27_RS10935 1993577..1993951 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AYN27_RS10940 1993955..1994827 + 873 WP_000879274.1 copper homeostasis membrane protein CopD -
AYN27_RS10945 1994840..1995181 + 342 WP_000976492.1 YebY family protein -
- 1995209..1995480 - 272 - - Antitoxin
- 1995339..1995442 + 104 - - Toxin
AYN27_RS10950 1995577..1996233 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AYN27_RS10955 1996234..1996425 - 192 WP_001296140.1 YebW family protein -
AYN27_RS10960 1996530..1996766 - 237 WP_001295499.1 DUF1480 family protein -
AYN27_RS10965 1996884..1998323 - 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98467 NZ_CP027380:1995339-1995442 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98467 NZ_CP027380:c1995480-1995209 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References