Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2088429..2088700 Replicon chromosome
Accession NZ_CP027366
Organism Escherichia coli strain 89-3156

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2088467..2088570 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2088429..2088700 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6P65_RS10835 2085586..2087025 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C6P65_RS10840 2087143..2087379 + 237 WP_001295499.1 DUF1480 family protein -
C6P65_RS10845 2087484..2087675 + 192 WP_001296140.1 YebW family protein -
C6P65_RS10850 2087676..2088332 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2088429..2088700 + 272 - - Antitoxin
- 2088467..2088570 - 104 - - Toxin
C6P65_RS10855 2088728..2089069 - 342 WP_000976492.1 YebY family protein -
C6P65_RS10860 2089082..2089954 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6P65_RS10865 2089958..2090332 - 375 WP_000204699.1 CopC domain-containing protein YobA -
C6P65_RS10870 2090471..2090701 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C6P65_RS10875 2090803..2091459 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6P65_RS10880 2091483..2092145 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - stx2B / stx2A 2087400..2171027 83627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98352 NZ_CP027366:c2088570-2088467 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98352 NZ_CP027366:2088429-2088700 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References