Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2718216..2718852 Replicon chromosome
Accession NZ_CP027365
Organism Acinetobacter radioresistens strain DSSKY-A-001

Toxin (Protein)


Gene name cptA Uniprot ID A0A8H2JZL1
Locus tag C6I29_RS12715 Protein ID WP_034669920.1
Coordinates 2718216..2718602 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8H2JY97
Locus tag C6I29_RS12720 Protein ID WP_034669918.1
Coordinates 2718595..2718852 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6I29_RS12700 2713512..2715791 - 2280 WP_034669925.1 TRAP transporter large permease subunit -
C6I29_RS12705 2715950..2716543 - 594 WP_034669923.1 rhombosortase -
C6I29_RS12710 2716621..2717736 - 1116 WP_034669922.1 hypothetical protein -
C6I29_RS12715 2718216..2718602 - 387 WP_034669920.1 hypothetical protein Toxin
C6I29_RS12720 2718595..2718852 - 258 WP_034669918.1 succinate dehydrogenase assembly factor 2 Antitoxin
C6I29_RS12725 2719036..2720208 + 1173 WP_034669917.1 acyl-CoA dehydrogenase family protein -
C6I29_RS12730 2720262..2721752 - 1491 WP_005407281.1 NAD(P)/FAD-dependent oxidoreductase -
C6I29_RS12735 2721932..2722309 - 378 WP_005018373.1 50S ribosomal protein L17 -
C6I29_RS12740 2722328..2723335 - 1008 WP_005024445.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15220.66 Da        Isoelectric Point: 10.2575

>T98346 WP_034669920.1 NZ_CP027365:c2718602-2718216 [Acinetobacter radioresistens]
MVKQCFKLKPSRMAIMVQLSLLLGLLILFYSLLPLGLWLLCSVIGLISYSLFLKTPRPVRFEYLDAEEWTLQFCKAKHLD
RVVIRKIIDHQLYIVIYFQKNQVKPLVIWSDQLSLVYWKKLKMLAKLY

Download         Length: 387 bp

>T98346 NZ_CP027365:c2718602-2718216 [Acinetobacter radioresistens]
ATGGTTAAGCAGTGTTTTAAGCTGAAACCTAGCCGCATGGCTATTATGGTTCAGCTTTCTTTACTACTCGGTTTGCTGAT
TTTGTTCTATTCACTACTACCGTTGGGACTATGGCTACTCTGTTCTGTCATTGGTTTGATAAGTTATAGCTTATTTTTAA
AAACGCCGCGTCCTGTACGCTTTGAATATCTAGATGCTGAAGAATGGACTCTTCAGTTCTGTAAAGCCAAACACTTAGAT
CGTGTTGTGATTCGAAAGATAATTGATCATCAACTTTATATTGTAATTTATTTTCAGAAAAATCAGGTTAAACCCTTGGT
TATCTGGAGTGATCAATTGTCTCTTGTATACTGGAAAAAATTAAAAATGTTAGCCAAGCTATATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10223.73 Da        Isoelectric Point: 4.5925

>AT98346 WP_034669918.1 NZ_CP027365:c2718852-2718595 [Acinetobacter radioresistens]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKQYYLQADAEEKATFAELVAQEDPDLLDWFMEVSEPPRPEMKQLIIKLK
HYIHG

Download         Length: 258 bp

>AT98346 NZ_CP027365:c2718852-2718595 [Acinetobacter radioresistens]
ATGTCTGAAGAAATGACTTTGGAAGAACGTAAAGTAATTTACCGTGCACGCCGGGGACTAAAAGAAATTGATGTATATTT
TGACCCTTATGTAAAACAATATTATTTACAAGCTGATGCGGAAGAAAAAGCCACCTTCGCCGAGCTCGTCGCACAGGAAG
ACCCTGATCTTCTAGACTGGTTTATGGAGGTTTCTGAACCCCCACGTCCGGAGATGAAACAGCTAATTATTAAACTTAAA
CATTATATCCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References