Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4423313..4423547 | Replicon | chromosome |
| Accession | NZ_CP027361 | ||
| Organism | Escherichia coli strain 2014C-4639 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4423314..4423417 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4423313..4423547 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RR62_RS22540 | 4420512..4421321 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| RR62_RS22545 | 4421378..4421572 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| RR62_RS22550 | 4421565..4421753 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 4421571..4421749 | - | 179 | NuclAT_1 | - | - |
| - | 4421571..4421749 | - | 179 | NuclAT_1 | - | - |
| - | 4421571..4421749 | - | 179 | NuclAT_1 | - | - |
| - | 4421571..4421749 | - | 179 | NuclAT_1 | - | - |
| RR62_RS22555 | 4421860..4422141 | + | 282 | WP_001443927.1 | excisionase | - |
| RR62_RS22560 | 4422107..4423222 | + | 1116 | WP_001189089.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4423313..4423547 | + | 235 | - | - | Antitoxin |
| - | 4423314..4423417 | - | 104 | - | - | Toxin |
| RR62_RS22565 | 4423575..4423916 | - | 342 | WP_000976492.1 | YebY family protein | - |
| RR62_RS22570 | 4423929..4424798 | - | 870 | WP_032341845.1 | copper homeostasis membrane protein CopD | - |
| RR62_RS22575 | 4424802..4425176 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| RR62_RS22580 | 4425315..4425545 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| RR62_RS22585 | 4425647..4426303 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| RR62_RS22590 | 4426327..4426989 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleC | 4371193..4429046 | 57853 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98312 NZ_CP027361:c4423417-4423314 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98312 NZ_CP027361:4423313-4423547 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
