Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 675931..676202 Replicon chromosome
Accession NZ_CP027355
Organism Escherichia coli strain 2013C-4991

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 676061..676164 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 675931..676202 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6P55_RS03770 672486..673148 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6P55_RS03775 673172..673828 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6P55_RS03780 673930..674160 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6P55_RS03785 674299..674673 + 375 WP_000168736.1 CopC domain-containing protein YobA -
C6P55_RS03790 674677..675549 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
C6P55_RS03795 675562..675903 + 342 WP_000976472.1 YebY family protein -
- 675931..676202 - 272 - - Antitoxin
- 676061..676164 + 104 - - Toxin
C6P55_RS03800 676299..676955 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
C6P55_RS03805 676956..677147 - 192 WP_001313035.1 YebW family protein -
C6P55_RS03810 677252..677488 - 237 WP_001295499.1 DUF1480 family protein -
C6P55_RS03815 677606..679045 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - stx2A / stx2B / nleC 603566..692026 88460


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98251 NZ_CP027355:676061-676164 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98251 NZ_CP027355:c676202-675931 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References