Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1394462..1394696 | Replicon | chromosome |
| Accession | NZ_CP027352 | ||
| Organism | Escherichia coli strain 2012C-4606 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1394463..1394566 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1394462..1394696 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AYN42_RS08395 | 1391661..1392470 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| AYN42_RS08400 | 1392527..1392721 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| AYN42_RS08405 | 1392714..1392902 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1392720..1392898 | - | 179 | NuclAT_1 | - | - |
| - | 1392720..1392898 | - | 179 | NuclAT_1 | - | - |
| - | 1392720..1392898 | - | 179 | NuclAT_1 | - | - |
| - | 1392720..1392898 | - | 179 | NuclAT_1 | - | - |
| AYN42_RS08410 | 1393009..1393290 | + | 282 | WP_001443927.1 | excisionase | - |
| AYN42_RS08415 | 1393256..1394371 | + | 1116 | WP_001189089.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1394462..1394696 | + | 235 | - | - | Antitoxin |
| - | 1394463..1394566 | - | 104 | - | - | Toxin |
| AYN42_RS08420 | 1394724..1395065 | - | 342 | WP_000976492.1 | YebY family protein | - |
| AYN42_RS08425 | 1395078..1395947 | - | 870 | WP_032341845.1 | copper homeostasis membrane protein CopD | - |
| AYN42_RS08430 | 1395951..1396325 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| AYN42_RS08435 | 1396464..1396694 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AYN42_RS08440 | 1396796..1397452 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| AYN42_RS08445 | 1397476..1398138 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 1340496..1400195 | 59699 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98224 NZ_CP027352:c1394566-1394463 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98224 NZ_CP027352:1394462-1394696 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
