Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2913332..2913603 Replicon chromosome
Accession NZ_CP027342
Organism Escherichia coli strain 2014C-4587

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2913462..2913565 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2913332..2913603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6N23_RS14955 2909887..2910549 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6N23_RS14960 2910573..2911229 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6N23_RS14965 2911331..2911561 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C6N23_RS14970 2911700..2912074 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C6N23_RS14975 2912078..2912950 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
C6N23_RS14980 2912963..2913304 + 342 WP_000976472.1 YebY family protein -
- 2913332..2913603 - 272 - - Antitoxin
- 2913462..2913565 + 104 - - Toxin
C6N23_RS14985 2913700..2914356 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
C6N23_RS14990 2914357..2914548 - 192 WP_001296140.1 YebW family protein -
C6N23_RS14995 2914653..2914889 - 237 WP_001295499.1 DUF1480 family protein -
C6N23_RS15000 2915007..2916446 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98133 NZ_CP027342:2913462-2913565 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98133 NZ_CP027342:c2913603-2913332 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References