Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1578172..1578406 | Replicon | chromosome |
| Accession | NZ_CP027331 | ||
| Organism | Escherichia coli strain 2013C-3277 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1578173..1578276 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1578172..1578406 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MJ63_RS08925 | 1575370..1576179 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| MJ63_RS08930 | 1576236..1576430 | + | 195 | WP_050439817.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| MJ63_RS08935 | 1576423..1576611 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1576429..1576607 | - | 179 | NuclAT_1 | - | - |
| - | 1576429..1576607 | - | 179 | NuclAT_1 | - | - |
| - | 1576429..1576607 | - | 179 | NuclAT_1 | - | - |
| - | 1576429..1576607 | - | 179 | NuclAT_1 | - | - |
| MJ63_RS08940 | 1576718..1576999 | + | 282 | WP_001443927.1 | excisionase | - |
| MJ63_RS08945 | 1576965..1578041 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1578172..1578406 | + | 235 | - | - | Antitoxin |
| - | 1578173..1578276 | - | 104 | - | - | Toxin |
| MJ63_RS08950 | 1578434..1578775 | - | 342 | WP_000976492.1 | YebY family protein | - |
| MJ63_RS08955 | 1578788..1579660 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| MJ63_RS08960 | 1579664..1580038 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| MJ63_RS08965 | 1580177..1580407 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| MJ63_RS08970 | 1580509..1581165 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| MJ63_RS08975 | 1581189..1581851 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | espFu/tccP | 1531673..1583908 | 52235 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98027 NZ_CP027331:c1578276-1578173 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98027 NZ_CP027331:1578172-1578406 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
