Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 261571..261839 Replicon chromosome
Accession NZ_CP027319
Organism Escherichia coli strain 2014C-3084

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 261698..261801 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 261571..261839 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAG01_RS01485 258124..258786 - 663 WP_000944252.1 exodeoxyribonuclease X -
AAG01_RS01490 258810..259466 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
AAG01_RS01495 259568..259798 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AAG01_RS01500 259937..260311 + 375 WP_000168738.1 CopC domain-containing protein YobA -
AAG01_RS01505 260315..261187 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
AAG01_RS01510 261200..261541 + 342 WP_000976475.1 YebY family protein -
- 261571..261839 - 269 - - Antitoxin
- 261698..261801 + 104 - - Toxin
AAG01_RS01515 261936..262592 + 657 WP_000812714.1 protein-serine/threonine phosphatase -
AAG01_RS01520 262593..262784 - 192 WP_001313035.1 YebW family protein -
AAG01_RS01525 262889..263125 - 237 WP_001295499.1 YebV family protein -
AAG01_RS01530 263243..264682 - 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - stx2A / stx2B / nleC 177447..277678 100231


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T97919 NZ_CP027319:261698-261801 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT97919 NZ_CP027319:c261839-261571 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References