Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4755929..4756521 Replicon chromosome
Accession NZ_CP027300
Organism Serratia marcescens strain SGAir0764

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag C1N78_RS22880 Protein ID WP_049300714.1
Coordinates 4756171..4756521 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag C1N78_RS22875 Protein ID WP_049300713.1
Coordinates 4755929..4756177 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1N78_RS22855 4751749..4752087 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
C1N78_RS22860 4752084..4753391 + 1308 WP_110147480.1 6-phospho-beta-glucosidase -
C1N78_RS22865 4753462..4754442 + 981 WP_016930354.1 LacI family transcriptional regulator -
C1N78_RS22870 4754634..4755818 + 1185 WP_004930336.1 MFS transporter TsgA -
C1N78_RS22875 4755929..4756177 + 249 WP_049300713.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
C1N78_RS22880 4756171..4756521 + 351 WP_049300714.1 type II toxin-antitoxin system ChpB family toxin Toxin
C1N78_RS22885 4756518..4757801 - 1284 WP_060441380.1 cytosine deaminase -
C1N78_RS22895 4758090..4760639 + 2550 WP_110147482.1 nitrite reductase large subunit NirB -
C1N78_RS22900 4760636..4760962 + 327 WP_016930361.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12404.41 Da        Isoelectric Point: 11.5657

>T97795 WP_049300714.1 NZ_CP027300:4756171-4756521 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T97795 NZ_CP027300:4756171-4756521 [Serratia marcescens]
ATGGTGAAGCGCCCCGTTTTTCAGCGCGGAGATCTTATCCGGGTCAGCCTGAATCCCGTGGTTGGCCGTGAGCAGCAAGG
CGACTTTCGTCCGGCACTGGTGCTCTCTCCCCGCGAGTTTAATGCGTTGGGCATGGTGCTGGTCGCCCCTATTTCGCAAG
GGGCTAATTTTGCCCGTACAGCGGGTTTCACCGTCAGCCTGAGCGGGAGCGGCACCGCAACGCAGGGCGTCATCTTGATC
AACCAGGTTCGCATGATGGATCTGGCCGGGCGCAGCGCGCAATTCATTGAACGAGCCCCTGGCGAAGTCATCGCCGACGC
GCTGGCGCGGCTTCAGGCAATCATCGACTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9069.53 Da        Isoelectric Point: 4.5026

>AT97795 WP_049300713.1 NZ_CP027300:4755929-4756177 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT97795 NZ_CP027300:4755929-4756177 [Serratia marcescens]
ATGAAAGTCTTTATCAAAAAATGGGGCAACAGCGCGGGAATGCTGGTGCCCTCAGCGCTAATGAACGAGCTGGAACTACA
GGTAGGTCAGGAAATGGACATGCAGGTCATCGATGGAGCGTTGGTCATTAAACCGGTTAAGAAACGCTATTCACTGCAGC
AATTGCTCGATGGCTGCGACGGTGAAGCGCCGGCCGCCGCAGACGACAACTGGGAACACATGCCGCCGGCGGGGAAAGAA
GTATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References